Objective To use deep sequencing to identify novel microRNAs (miRNAs) in human
osteoarthritic cartilage which have a functional role in chondrocyte phenotype or function …

Background Osteoarthritis (OA) is a multifactorial disease characterized by destruction of the
articular cartilage due to environmental, mechanical and genetic components. The genetics …

MicroRNAs are small double-stranded RNAs, which negatively regulate gene expression
and have been shown to have key roles in both chondrocyte development and cartilage …

Objective MicroRNA (miRNA) are a class of noncoding small RNAs that act as negative
regulators of gene expression. MiRNA exhibit tissue‐specific expression patterns, and …

Osteoarthritis is the most common degenerative joint disorder. MicroRNAs are gene
expression regulators that act post-transcriptionally to control tissue homeostasis. Microarray …

BACKGROUND: Expression profiles of microRNAs (miRNAs) can shape the repertoire of
proteins expressed in development, differentiation and diseases. This study aimed to identify …

This study aimed to identify the microRNAs associated with sclerotic status of subchondral
bone in the pathogenesis of osteoarthritis (OA). Total RNA was extracted from non-sclerotic …

Objective To evaluate the underlying function of microRNAs (miRNAs) in osteoarthritis (OA).
Design A bioinformatic analysis of miRNAs-OA studies was completed in multiple …

OBJECTIVE: To identify differentially expressed microRNAs (miRNAs) in human
osteoarthritic (OA) cartilage and bone tissue and to determine their relevance to chondrocyte …

Objective To use an in vitro model of chondrogenesis to identify microRNAs (miRNAs) with a
functional role in cartilage homeostasis. Methods The expression of miRNAs was measured …