[HTML][HTML] Osteoblast-chondrocyte interactions in osteoarthritis
DM Findlay, GJ Atkins - Current osteoporosis reports, 2014 - Springer
There is now general agreement that osteoarthritis (OA) involves all structures in the affected
joint, culminating in the degradation of the articular cartilage. It is appropriate to focus …
joint, culminating in the degradation of the articular cartilage. It is appropriate to focus …
[PDF][PDF] The role of the chondrocyte in osteoarthritis
MB Goldring - Arthritis & Rheumatism: Official Journal of the …, 2000 - academia.edu
Osteoarthritis (OA) is a slowly progressive degenerative disease characterized by gradual
loss of articular cartilage. Since the OA lesion is often localized to weight-bearing cartilage …
loss of articular cartilage. Since the OA lesion is often localized to weight-bearing cartilage …
Microenvironment in subchondral bone: predominant regulator for the treatment of osteoarthritis
W Hu, Y Chen, C Dou, S Dong - Annals of the Rheumatic Diseases, 2021 - ard.bmj.com
Osteoarthritis (OA) is a degenerative joint disease in the elderly. Although OA has been
considered as primarily a disease of the articular cartilage, the participation of subchondral …
considered as primarily a disease of the articular cartilage, the participation of subchondral …
Alterations in periarticular bone and cross talk between subchondral bone and articular cartilage in osteoarthritis
SR Goldring - Therapeutic advances in musculoskeletal …, 2012 - journals.sagepub.com
The articular cartilage and the subchondral bone form a biocomposite that is uniquely
adapted to the transfer of loads across the diarthrodial joint. During the evolution of the …
adapted to the transfer of loads across the diarthrodial joint. During the evolution of the …
[HTML][HTML] Osteoarthritis year 2012 in review: biology
PM Van der Kraan - Osteoarthritis and Cartilage, 2012 - Elsevier
This review focuses on recent findings in pathobiology of osteoarthritis (OA). The progress in
this field will be illustrated based on three questions; 1. What factors maintain or alter the …
this field will be illustrated based on three questions; 1. What factors maintain or alter the …
Subchondral bone and osteoarthritis: biological and cellular aspects
Y Henrotin, L Pesesse, C Sanchez - Osteoporosis International, 2012 - Springer
The subchondral bone is involved in the pathophysiology of osteoarthritis (OA), both by
biochemical and mechanical pathways. Overloaded OA subchondral bone osteoblasts …
biochemical and mechanical pathways. Overloaded OA subchondral bone osteoblasts …
Changes in the osteochondral unit during osteoarthritis: structure, function and cartilage–bone crosstalk
SR Goldring, MB Goldring - Nature Reviews Rheumatology, 2016 - nature.com
In diarthrodial joints, the articular cartilage, calcified cartilage, and subchondral cortical and
trabecular bone form a biocomposite—referred to as the osteochondral unit—that is …
trabecular bone form a biocomposite—referred to as the osteochondral unit—that is …
[PDF][PDF] Pathophysiology of osteoarthritis
J Martel-Pelletier - Osteoarthritis and cartilage, 1998 - core.ac.uk
Although cartilage degeneration characterizes human osteoarthritis (OA), changes also
involve the participation of the synovial membrane and the subchondral bone. In this review …
involve the participation of the synovial membrane and the subchondral bone. In this review …
[HTML][HTML] How are aging and osteoarthritis related?
Osteoarthritis is the most prevalent degenerative joint disease and one of the leading
causes of physical impairment in the world's aging population. The human lifespan has …
causes of physical impairment in the world's aging population. The human lifespan has …
[PDF][PDF] Changes in subchondral bone early in the development of osteoarthritis
SC Mastbergen, F Lafeber - Arthritis & Rheumatism, 2011 - researchgate.net
Osteoarthritis (OA) is a slowly progressive degenerative joint disorder characterized by
cartilage damage, changes in periarticular bone including osteophyte formation and a …
cartilage damage, changes in periarticular bone including osteophyte formation and a …