Harnessing Biomaterials to Study and Direct Antigen-Specific Immunotherapy

C Edwards, ST Carey, CM Jewell - ACS Applied Bio Materials, 2023 - ACS Publications
Immunotherapies are an evolving treatment paradigm for addressing cancer, autoimmunity,
and infection. While exciting, most of the existing therapies are limited by their specificity─ …

Biomaterials as tools to decode immunity

HB Eppler, CM Jewell - Advanced Materials, 2020 - Wiley Online Library
The immune system has remarkable capabilities to combat disease with exquisite selectivity.
This feature has enabled vaccines that provide protection for decades and, more recently …

Engineered materials for cancer immunotherapy

AS Cheung, DJ Mooney - Nano today, 2015 - Elsevier
Immunotherapy is a promising treatment modality for cancer as it can promote specific and
durable anti-cancer responses. However, limitations to current approaches remain …

Immunologically effective biomaterials

Q Wei, Y Su, H Xin, L Zhang, J Ding… - ACS Applied Materials & …, 2021 - ACS Publications
Immunoregulation represents a booming field of biomaterial design. The unique physical
and chemical properties of biomaterials offer tremendous opportunities for development …

Biomaterials for enhancing anti-cancer immunity

ST Koshy, DJ Mooney - Current opinion in biotechnology, 2016 - Elsevier
Highlights•Biomaterials can potentially improve the safety and efficacy of cancer
immunotherapy.•Biomaterials scaffolds can program immune cell function in peripheral …

Harnessing innate immunity using biomaterials for cancer immunotherapy

DY Lee, K Huntoon, Y Wang, W Jiang… - Advanced …, 2021 - Wiley Online Library
The discovery of immune checkpoint blockade has revolutionized the field of immuno‐
oncology and established the foundation for developing various new therapies that can …

Harnessing biomaterial architecture to drive anticancer innate immunity

MA Davis, E Cho, MH Teplensky - Journal of Materials Chemistry B, 2023 - pubs.rsc.org
Immunomodulation is a powerful therapeutic approach that harnesses the body's own
immune system and reprograms it to treat diseases, such as cancer. Innate immunity is key …

Engineered multifunctional nano‐and biological materials for cancer immunotherapy

A Brouillard, N Deshpande… - Advanced Healthcare …, 2021 - Wiley Online Library
Cancer immunotherapy is set to emerge as the future of cancer therapy. However, recent
immunotherapy trials in different cancers have yielded sub‐optimal results, with durable …

[HTML][HTML] Targeted modulation of immune cells and tissues using engineered biomaterials

P Yousefpour, K Ni, DJ Irvine - Nature reviews bioengineering, 2023 - nature.com
Therapies modulating the immune system offer the prospect of treating a wide range of
conditions including infectious diseases, cancer and autoimmunity. Biomaterials can …

Biomaterial strategies for immunomodulation

NA Hotaling, L Tang, DJ Irvine… - Annual review of …, 2015 - annualreviews.org
Strategies to enhance, suppress, or qualitatively shape the immune response are of
importance for diverse biomedical applications, such as the development of new vaccines …