Perturbation of natural killer cell function and receptors during HIV infection

KA Eger, D Unutmaz - Trends in microbiology, 2004 - cell.com
Natural killer (NK) cells play an important role in innate host defenses against a variety of
pathogens. A recent report described striking perturbations in the expression of NK cell …

Natural killer cells in HIV-1 infection: dichotomous effects of viremia on inhibitory and activating receptors and their functional correlates

D Mavilio, J Benjamin, M Daucher… - Proceedings of the …, 2003 - National Acad Sciences
Natural killer (NK) cells play a central role in host defense against various pathogens.
Functional defects of NK cells in HIV-1 infection as a direct effect of abnormal expression or …

Role of natural killer cells in HIV pathogenesis

J Ward, E Barker - Current HIV/AIDS Reports, 2008 - Springer
Although the majority of research on immune cell recognition of HIV-infected cells has
focused on CD8+ T cells with an eye towards vaccine development, innate immune …

Natural killer cells in HIV-1 infection and therapy

J Mikulak, F Oriolo, E Zaghi, C Di Vito, D Mavilio - Aids, 2017 - journals.lww.com
Natural killer (NK) cells are important effectors of innate immunity playing a key role in the
eradication and clearance of viral infections. Over the recent years, several studies have …

NK Cells in Protection from HIV Infection

NF Bernard, K Alsulami, E Pavey, FP Dupuy - Viruses, 2022 - mdpi.com
Some people, known as HIV-exposed seronegative (HESN) individuals, remain uninfected
despite high levels of exposure to HIV. Understanding the mechanisms underlying their …

Negative regulation and protective function of natural killer cells in HIV infection: two sides of a coin

Y Sun, J Zhou, Y Jiang - Frontiers in Immunology, 2022 - frontiersin.org
Natural killer (NK) cells play an important immunologic role, targeting tumors and virus-
infected cells; however, NK cells do not impede the progression of human immunodeficiency …

Natural killer cell function in patients with acquired immunodeficiency syndrome and related diseases

BG Brenner, A Dascal, RG Margolese… - Journal of Leukocyte …, 1989 - Wiley Online Library
This review describes current knowledge of changes in natural killer (NK) cell function in
acquired immunodeficiency syndrome (AIDS)‐related disorders, vis‐à‐vis associated …

NK cells in HIV infection: paradigm for protection or targets for ambush

AS Fauci, D Mavilio, S Kottilil - Nature Reviews Immunology, 2005 - nature.com
Natural killer cells are a crucial component of the innate immune response to certain
tumours and to various viruses, fungi, parasites and bacteria. HIV has infected more than 60 …

Characterization of CD56/CD16+ natural killer (NK) cells: A highly dysfunctional NK subset expanded in HIV-infected viremic individuals

D Mavilio, G Lombardo, J Benjamin… - Proceedings of the …, 2005 - National Acad Sciences
Natural killer (NK) cells are an important component of the innate immune response against
viral infections. NK cell-mediated cytolytic activity is defective in HIV-infected individuals with …

Natural killer cells in HIV-1 infection: role of NK cell-mediated non-cytolytic mechanisms in pathogenesis of HIV-1 infection

S Kottilil - 2003 - nopr.niscpr.res.in
Natural killer (NK) cells exhibit both cytolytic and non-cytolytic effector functions against HIV-
infected targets. Their precise rule in immunopathogenesis of HIV-1 infection is, yet to be …