Vascular blood flow and its distribution among different vascular beds are regulated by
changes in microvascular tone. Nitric oxide (NO) plays a key role in the local paracrine …

Nitric oxide (NO) has multiple important actions that contribute to the maintenance of
vascular homeostasis. NO is synthesized by three different isoforms of NO synthase (NOS) …

Background—Nitric oxide (NO) has a pivotal role in the regulation of vascular tone and
blood flow, with dysfunctional release contributing to disease pathophysiology. These effects …

The family of nitric oxide synthases (NOS) has significant importance in various
physiological mechanisms and is also involved in many pathological processes. Three NOS …

Nitric oxide (NO) has multiple important actions that contribute to the maintenance of
vascular homeostasis. NO is synthesized by three different isoforms of NO synthase (NOS) …

Background—Nitric oxide (NO)–mediated local regulation of vascular tone is considered to
involve endothelial NO synthase (eNOS). However, we recently reported that human …

ABSTRACT NO, produced by the endothelium, is a modulator of vascular inflammation.
Traditionally, eNOS was believed to be the primary source of NO in the endothelium …

In 1980, Furchgott and Zawadzki demonstrated that the relaxation of vascular smooth
muscle cells in response to acetylcholine is dependent on the anatomical integrity of the …

As the first discovered gaseous signaling molecule, nitric oxide (NO) affects a number of
cellular processes, including those involving vascular cells. This brief review summarizes …

This review describes and summarizes the role of neuronal nitric oxide synthase (nNOS) on
the central nervous system, particularly on brain regions such as the ventrolateral medulla …