Antibodies and antisense oligonucleotide for probing the distribution and putative functions of central 5-HT6 receptors
M Hamon, E Doucet, K Lefèvre, MC Miquel… - …, 1999 - Elsevier
Among the recently cloned serotonin (5-hydroxytryptamine, 5-HT) receptors, the 5-HT6
subtype is of special interest for at least two reasons: 1) it is abundant in limbic areas which …
subtype is of special interest for at least two reasons: 1) it is abundant in limbic areas which …
Immuno-localization of serotonin 5-HT6 receptor-like material in the rat central nervous system
C Gérard, MP Martres, K Lefèvre, MC Miquel, D Vergé… - Brain research, 1997 - Elsevier
In order to map the recently cloned serotonin 5-HT6 receptor in the rat brain and spinal cord,
polyclonal antibodies were raised against a synthetic octadecapeptide corresponding to a …
polyclonal antibodies were raised against a synthetic octadecapeptide corresponding to a …
Localization of 5-HT7 receptors in rat brain by immunocytochemistry, in situ hybridization, and agonist stimulated cFos expression
JF Neumaier, TJ Sexton, J Yracheta, AM Diaz… - Journal of chemical …, 2001 - Elsevier
5-HT7 receptors are recently identified members of the serotonin receptor family that have
moderate to high affinity for several important psychotropic drugs. However, the lack of …
moderate to high affinity for several important psychotropic drugs. However, the lack of …
Distribution of serotonin receptor 5-HT6 mRNA in rat neuronal subpopulations: a double in situ hybridization study
L Helboe, J Egebjerg, IEM De Jong - Neuroscience, 2015 - Elsevier
Abstract The 5-HT 6 receptor (5-HT 6 R) is almost exclusively expressed in the brain and
has emerged as a promising target for cognitive disorders, including Alzheimer's disease. In …
has emerged as a promising target for cognitive disorders, including Alzheimer's disease. In …
Localization of 5-ht5A receptor-like immunoreactivity in the rat brain
KR Oliver, AM Kinsey, A Wainwright… - Brain research, 2000 - Elsevier
5-Hydroxytryptamine exerts modulatory physiological effects on both the central and
peripheral nervous systems by activation of discrete receptor families. 5-ht5A is among the …
peripheral nervous systems by activation of discrete receptor families. 5-ht5A is among the …
Differential agonist-mediated internalization of the human 5-hydroxytryptamine 7 receptor isoforms
CR Guthrie, AT Murray, AA Franklin… - Journal of Pharmacology …, 2005 - ASPET
The human 5-hydroxytryptamine 7 (5-HT7) serotonin receptor is a class A G-protein coupled
receptor that has three isoforms, 5-HT7 (a), 5-HT7 (b), and 5-HT7 (d), which are produced by …
receptor that has three isoforms, 5-HT7 (a), 5-HT7 (b), and 5-HT7 (d), which are produced by …
Distribution of the 5-HT5A serotonin receptor mRNA in the human brain
M Pasqualetti, M Ori, I Nardi, M Castagna… - Molecular brain …, 1998 - Elsevier
The 5-HT5A receptor is a member of a new subfamily of serotonin [5-hydroxytryptamine (5-
HT)] receptors recently cloned from the human and rodent brain. The role of this receptor in …
HT)] receptors recently cloned from the human and rodent brain. The role of this receptor in …
Cellular and subcellular immunolocalization of the type 3 serotonin receptor in the rat central nervous system
M Morales, E Battenberg, L de Lecea, PP Sanna… - Molecular brain …, 1996 - Elsevier
We developed and characterized 14 polyclonal antibodies against peptides whose
sequences were predicted from the type 3 serotonin receptor subunit A (5-HT3R-A) cDNA …
sequences were predicted from the type 3 serotonin receptor subunit A (5-HT3R-A) cDNA …
5-ht6 Receptors as Emerging Targets for Drug Discovery
TA Branchek, TP Blackburn - Annual review of pharmacology …, 2000 - annualreviews.org
5-ht6 receptors are the latest serotonin receptors to be identified by molecular cloning. Their
high affinity for a wide range of drugs used in psychiatry, coupled with their intriguing …
high affinity for a wide range of drugs used in psychiatry, coupled with their intriguing …
[HTML][HTML] Neuropharmacological profile of novel and selective 5-HT6 receptor agonists: WAY-181187 and WAY-208466
LE Schechter, Q Lin, DL Smith, G Zhang… - …, 2008 - nature.com
One of the most recently identified serotonin (5-hydroxytryptamine (5-HT)) receptor subtypes
is the 5-HT 6 receptor. Although in-depth localization studies reveal an exclusive distribution …
is the 5-HT 6 receptor. Although in-depth localization studies reveal an exclusive distribution …