Iatrogenic nerve injury represents one of the most feared surgical complications and
remains a major morbidity across many surgical specialties. Currently, no clinically …

Objective: This review details the agents for fluorescence-guided nerve imaging in both
preclinical and clinical use to identify factors important in selecting nerve-specific fluorescent …

Iatrogenic nerve injury significantly affects surgical outcomes. Although intraoperative
neuromonitoring is utilized, nerve identification remains challenging and the success of …

Accidental transection or injury of nerves during surgeries leads to severe patient morbidity
and lowers the life quality of patients. The current imaging modality for nerves, such as …

Fluorescence guided surgery (FGS) has fueled the development of novel technologies
aimed at maximizing the utility of fluorescence imaging to help clinicians diagnose and in …

Nerve-binding fluorophores with near-infrared (NIR; 650 to 900 nm) emission could reduce
iatrogenic nerve injury rates by providing surgeons precise, real-time visualization of the …

Nerve damage is a major morbidity associated with numerous surgical interventions. Yet,
nerve visualization continues to challenge even the most experienced surgeons. A nerve …

A fundamental goal of many surgeries is nerve preservation, as inadvertent injury can lead
to patient morbidity including numbness, pain, localized paralysis and incontinence. Nerve …

Near‐infrared (NIR) fluorescence imaging can provide real‐time navigation for surgeons to
discriminate boundaries between lesions and healthy tissue, which serves as a promising …

Background Despite significant improvements in preoperative workup and surgical
planning, surgeons often rely on their eyes and hands during surgery. Although this can be …