Trans‐Cinnamaldehyde from Cinnamomum zeylanicum Bark Essential Oil Reduces the Clindamycin Resistance of Clostridium difficile in vitro

AR Shahverdi, HR Monsef‐Esfahani… - Journal of Food …, 2007 - Wiley Online Library
Therapy with antimicrobial drugs, such as clindamycin, that perturb the intestinal flora but fail
to inhibit growth of other microorganisms can permit the proliferation of Clostridium difficile …

Carvacrol reduces Clostridium difficile sporulation and spore outgrowth in vitro

S Mooyottu, G Flock… - Journal of Medical …, 2017 - microbiologyresearch.org
Purpose. Clostridium difficile is an anaerobic spore-forming pathogen that causes a serious
toxin-mediated enteric disease in humans. Therapeutic agents that are capable of reducing …

Alternative strategies for Clostridium difficile infection

MP Bauer, JT van Dissel - International journal of antimicrobial agents, 2009 - Elsevier
Although antibiotics are generally effective in achieving symptomatic recovery from
Clostridium difficile infection, the disease frequently relapses, partly because antibiotics not …

[PDF][PDF] Natural alternative remedies in the background of updated recommendations for the prophylactic and therapeutic approach of clostridium difficile infections

M Georgescu, O Ginghina, S Raita, D Tapaloaga… - …, 2018 - farmaciajournal.com
Clostridium difficile infection (CDI) remains one of the greatest concerns in current
worldwide medical practice. Its incidence, severity and patient susceptibility range have …

[HTML][HTML] Discovery of a novel natural product inhibitor of Clostridioides difficile with potent activity in vitro and in vivo

R Pal, MN Seleem - Plos one, 2022 - journals.plos.org
Clostridioides difficile infection is a global health threat and remains the primary cause of
hospital-acquired infections worldwide. The burgeoning incidence and severity of infections …

Progress in the discovery of treatments for C. difficile infection: a clinical and medicinal chemistry review

LS Tsutsumi, YB Owusu, JG Hurdle… - Current topics in …, 2014 - ingentaconnect.com
Clostridium difficile is an anaerobic, Gram-positive pathogen that causes C. difficile infection,
which results in significant morbidity and mortality. The incidence of C. difficile infection in …

[PDF][PDF] Effect of Lactobacillus plantarum strains on clinical isolates of Clostridium difficile in vitro

M Ratsep, P Naaber, S Koljalg, I Smidt, E Shkut… - J. Probiotics …, 2014 - eemb.ut.ee
Probiotic bacteria are proposed for prevention of Clostridium difficile associated diarrhea.
The aim of this in vitro study was to evaluate the influence of five Lactobacillus plantarum …

In vitro inhibition of Clostridium difficile by commercial probiotics: a microcalorimetric study

M Fredua-Agyeman, P Stapleton, AW Basit… - International journal of …, 2017 - Elsevier
The aim of the study was to investigate the influence of some commercial probiotics on the
growth of Clostridium difficile using isothermal microcalorimetry, a technique which can …

Future novel therapeutic agents for Clostridium difficile infection

HL Koo, KW Garey, HL DuPont - Expert opinion on investigational …, 2010 - Taylor & Francis
Importance of the field: Clostridium difficile is the most important definable cause of
healthcare acquired diarrhea. The increasing incidence and mortality associated with this …

Novel antibiotics in development to treat Clostridium difficile infection

E Bassères, BT Endres, KM Dotson… - Current Opinion in …, 2017 - journals.lww.com
Many of these new antibiotics display almost ideal properties for antibiotics directed against
CDI. Despite these properties, not all clinical development of these compounds has been …