Efficacy and safety of duloxetine for treatment of fibromyalgia in patients with or without major depressive disorder: results from a 6-month, randomized, double-blind …

IJ Russell, PJ Mease, TR Smith, DK Kajdasz… - Pain, 2008 - Elsevier
The primary objectives of this study were to assess the efficacy and safety of duloxetine for
reducing pain severity in fibromyalgia patients with or without current major depressive …

Efficacy of duloxetine in patients with fibromyalgia: pooled analysis of 4 placebo-controlled clinical trials

LM Arnold, DJ Clauw, MM Wohlreich… - … care companion to …, 2009 - psychiatrist.com
Objective: To investigate the efficacy of duloxetine in the treatment of pain and improvement
in functional impairment and quality of life in patients with fibromyalgia from a pooled …

A double‐blind, multicenter trial comparing duloxetine with placebo in the treatment of fibromyalgia patients with or without major depressive disorder

LM Arnold, Y Lu, LJ Crofford… - … : Official Journal of …, 2004 - Wiley Online Library
Objective To assess the efficacy and safety of duloxetine, a serotonin and norepinephrine
reuptake inhibitor, in subjects with primary fibromyalgia, with or without current major …

A six-month double-blind, placebo-controlled, randomized clinical trial of duloxetine for the treatment of fibromyalgia

AS Chappell, LA Bradley, C Wiltse… - … Journal of General …, 2009 - Taylor & Francis
Objective: Assess the efficacy of duloxetine 60/120 mg (N= 162) once daily compared with
placebo (N= 168) in the treatment of patients with fibromyalgia, during six months of …

A randomized, double-blind, placebo-controlled trial of duloxetine in the treatment of women with fibromyalgia with or without major depressive disorder

LM Arnold, A Rosen, YL Pritchett, DN D'Souza… - Pain, 2005 - Elsevier
This was a 12-week, randomized, double-blind, placebo-controlled trial to assess the
efficacy and safety of duloxetine, a selective serotonin and norepinephrine reuptake …

Flexible dosed duloxetine in the treatment of fibromyalgia: a randomized, double-blind, placebo-controlled trial

LM Arnold, D Clauw, F Wang, J Ahl, PJ Gaynor… - The Journal of …, 2010 - jrheum.org
Objective. To investigate the efficacy of flexible dose duloxetine 60–120 mg/day on changes
in fibromyalgia (FM) symptoms assessed by the Patient Global Impression of Improvement …

Duloxetine for the treatment of fibromyalgia in women: pooled results from two randomized, placebo-controlled clinical trials

LM Arnold, YL Pritchett, DN D'Souza… - Journal of Women's …, 2007 - liebertpub.com
Background: To assess the efficacy (in particular, in pain, functional impairment, and quality
of life) and safety and tolerability (incidence of adverse events, discontinuation rates …

Comparative pain and mood effects in patients with comorbid fibromyalgia and major depressive disorder: secondary analyses of four pooled randomized controlled …

LB Marangell, DJ Clauw, E Choy, F Wang… - PAIN®, 2011 - Elsevier
The objective of this paper is to better understand the relationship of pain and mood in
patients with fibromyalgia and comorbid major depressive disorder (MDD). Pooled data from …

Duloxetine and other antidepressants in the treatment of patients with fibromyalgia

LM Arnold - Pain medicine, 2007 - academic.oup.com
Objective. To review the use of duloxetine, a new selective serotonin and norepinephrine
reuptake inhibitor (SNRI), and other antidepressants in the treatment of patients with …

Duloxetine, 60 mg once daily, for major depressive disorder: a randomized double-blind placebo-controlled trial

MJ Detke, Y Lu, DJ Goldstein, JR Hayes… - Journal of Clinical …, 2002 - psychiatrist.com
Background: Despite treatment advances, major depressive disorder (MDD) is still a
significant cause of morbidity and mortality. Current therapies frequently fall short of …