Cytochrome P450 isoenzyme mRNA expression pattern in human urinary bladder malignancies and normal urothelium.
A Brauers, E Manegold, R Buettner… - Cancer Detection and …, 2000 - europepmc.org
This study was designed to analyze the cytochrome P450 isoenzyme mRNA expression
pattern of transitional cell carcinomas of the bladder (N= 19) and normal urothelium (N= 10) …
pattern of transitional cell carcinomas of the bladder (N= 19) and normal urothelium (N= 10) …
Expression of xenobiotic metabolizing enzymes in tumours of the urinary bladder.
GI Murray, VE Taylor, JA McKay… - International journal …, 1995 - ncbi.nlm.nih.gov
The cytochromes P450, epoxide hydrolase and glutathione S-transferases are several of the
major groups of enzymes involved in the metabolism of xenobiotics and these enzymes may …
major groups of enzymes involved in the metabolism of xenobiotics and these enzymes may …
CYP4B1 is a possible risk factor for bladder cancer in humans
S Imaoka, Y Yoneda, T Sugimoto, T Hiroi… - Biochemical and …, 2000 - Elsevier
In experimental animals such as rats and rabbits, CYP4B1 has an important role in
mutagenic activation of procarcinogens in bladders. In human bladders, it is not clear …
mutagenic activation of procarcinogens in bladders. In human bladders, it is not clear …
Expression of cytochrome P450 enzymes CYP1A1, CYP1B1, CYP2E1 and CYP4B1 in cultured transitional cells from specimens of the human urinary tract and from …
PH Roos, R Belik, W Föllmann, GH Degen… - Archives of …, 2006 - Springer
Expression of cytochromes P450 CYP1A1, CYP1B1, CYP2E1 and CYP4B1 was analysed
on the transcript level in human urothelial cells obtained by various methods. As a source of …
on the transcript level in human urothelial cells obtained by various methods. As a source of …
Mutagenic activation of urinary bladder carcinogens by CYP4B1 and the presence of CYP4B1 in bladder mucosa
S Imaoka, Y Yoneda, T Matsnda, M Degawa… - Biochemical …, 1997 - Elsevier
We investigated the mutagenic activation of 2-naphthylamine (2-NA), 3, 2′-dimethyl-4-
aminobiphenyl (DMAB), and 3, 3′-dichlorobenzidine (DCB), bladder carcinogens, by renal …
aminobiphenyl (DMAB), and 3, 3′-dichlorobenzidine (DCB), bladder carcinogens, by renal …
Comparison of enzyme phenotypes in human bladder tumours and experimentally induced hyperplastic and neoplastic lesions of the rat urinary bladder: A combined …
H Tsuda, T Inoue, M Asamoto, S Fukushima, N Ito… - Virchows Archiv B, 1988 - Springer
The expression of a number of enzymes involved in drug metabolism, membrane function
etc. was compared in hyperplastic and neoplastic lesions of the rat bladder and in human …
etc. was compared in hyperplastic and neoplastic lesions of the rat bladder and in human …
Tumor-specific expression of cytochrome P450 CYP1B1
GI Murray, MC Taylor, MCE McFadyen, JA McKay… - Cancer research, 1997 - AACR
Abstract Cytochrome P450 CYP1B1 is a recently cloned dioxin-inducible form of the
cytochrome P450 family of xenobiotic metabolizing enzymes. An antibody raised against a …
cytochrome P450 family of xenobiotic metabolizing enzymes. An antibody raised against a …
Androgen regulation of CYP4B1 responsible for mutagenic activation of bladder carcinogens in the rat bladder: detection of CYP4B1 mRNA by competitive reverse …
S Imaoka, Y Yoneda, T Sugimoto, S Ikemoto, T Hiroi… - Cancer letters, 2001 - Elsevier
Significant sex differences exist among cases of bladder cancer in humans as well as in
experimental animals such as rats. Aromatic amines such as benzidine and 2 …
experimental animals such as rats. Aromatic amines such as benzidine and 2 …
Immunohistochemical localization of cytochrome P450 3A in human pulmonary carcinomas and normal bronchial tissue
KT Kivistö, HK Kroemer, P Fritz, A Linder… - Histochemistry and cell …, 1995 - Springer
The cytochrome P450 (CYP) enzymes metabolize drugs and other xenobiotics in liver and
also in some extrahepatic tissues. We have studied the expression and localization of …
also in some extrahepatic tissues. We have studied the expression and localization of …
Downregulation of the cytochrome P450 4B1 protein confers a poor prognostic factor in patients with urothelial carcinomas of upper urinary tracts and urinary bladder
JT Lin, TC Chan, CF Li, SKH Huan, YF Tian, PI Liang… - Apmis, 2019 - Wiley Online Library
The objective of this study was to examine the expression level of cytochrome P450 4B1
(CYP 4B1) protein and its clinical significance in specimens from patients with urothelial …
(CYP 4B1) protein and its clinical significance in specimens from patients with urothelial …