Quality of life assessment in trials of revascularization for chronic stable angina: insights from ORBITA and the implications of blinding

AN Nowbar, DP Francis, RK Al-Lamee - Cardiovascular drugs and therapy, 2022 - Springer
The main aims of therapy in chronic stable angina are to reduce the risk of myocardial
infarction and death and improve symptoms and quality of life (QoL). Unblinded trials have …

Comparative effectiveness of revascularization strategies in stable ischemic heart disease: current perspective and literature review

Z Fanari, SA Weiss, WS Weintraub - Expert Review of …, 2013 - Taylor & Francis
Percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) are
established strategies for coronary revascularization in the setting of ischemic heart disease …

[HTML][HTML] ORBITA: What Goes Around, Comes Around… Or Does It?

M Jackson, A Zaman - Interventional Cardiology Review, 2018 - ncbi.nlm.nih.gov
Current guidelines recommend percutaneous coronary intervention (PCI) in patients with
ongoing stable angina symptoms despite optimal medical therapy (OMT), although trials …

Unmet medical needs and therapeutic opportunities in stable angina

P Gabriel Steg, D Himbert - European Heart Journal …, 2005 - academic.oup.com
Stable angina is a frequent problem and it impacts on outcomes and quality of life. The
treatment of stable angina includes a wide array of tools, including medical therapy and …

The immediate impact of the Clinical Outcomes Utilizing Revascularization and Aggressive Drug Evaluation (COURAGE) trial on the management of stable angina

BD Atwater, J Oujiri, MR Wolff - … for Advances in the Treatment of …, 2009 - Wiley Online Library
Abstract Background The Clinical Outcomes Utilizing Revascularization and Aggressive
Drug Evaluation (COURAGE) trial confirmed that percutaneous coronary intervention is no …

[HTML][HTML] The ORBITA trial: A point of view

VD Oliveira, FR Giugni, EB Martins… - Revista da Associação …, 2018 - SciELO Brasil
Treatment of stable coronary artery disease (CAD) relies on improved prognosis and relief of
symptoms. National and international guidelines on CAD support the indication for …

Evidence-based management of stable ischemic heart disease: challenges and confusion

S Bangalore, DJ Maron, JS Hochman - JAMA, 2015 - jamanetwork.com
Everyyearapproximately1millionpercutaneo…-nary interventions (PCIs) are performed in the
United States and many more are performed worldwide, with a sizeableproportion (30 …

The initial management of stable angina in Europe, from the Euro Heart Survey: a description of pharmacological management and revascularization strategies …

CA Daly, F Clemens, JLL Sendon… - European heart …, 2005 - academic.oup.com
Aims In order to assess adherence to guidelines and international variability in
management, the Euro Heart Survey of Newly Presenting Angina prospectively studied …

[HTML][HTML] Publish in our journal

D Vivas - recintervcardiol.org
ANSWER: The 2 ORBITA studies aim to settle the debate on the utility of coronary
revascularization in patients with stable chronic angina and coronary artery lesions causing …

Initial strategy of revascularization versus optimal medical therapy for improving outcomes in ischemic heart disease: a review of the literature

AV Songco, SJ Brener - Current cardiology reports, 2012 - Springer
Defining optimal management of patients with stable coronary artery disease continues to
be a central area of debate. While it has been established that all patients with coronary …