Neurovascular protection of cilostazol in stroke‐prone spontaneous hypertensive rats associated with angiogenesis and pericyte proliferation

Y Omote, K Deguchi, S Kono, N Liu… - Journal of …, 2014 - Wiley Online Library
Stroke is the major cause of death and decrease in the activities of daily living. This study
sought to evaluate the effects of commonly used antiplatelet drugs on spontaneous cerebral …

Induction of infarct tolerance by platelet-derived growth factor against temporary focal ischemia

M Sakata, H Yanamoto, N Hashimoto, K Iihara… - Brain research, 1998 - Elsevier
Nerve growth factor, brain-derived neurotrophic factor, and other neurotrophic factors have
been reported to have neuroprotective effects against global ischemia. To investigate …

Involvement of thrombin and mitogen-activated protein kinase pathways in hemorrhagic brain injury

M Ohnishi, H Katsuki, S Fujimoto, M Takagi… - Experimental …, 2007 - Elsevier
Thrombin is thought to play an important role in brain damage associated with intracerebral
hemorrhage (ICH). We previously showed that activation of mitogen-activated protein (MAP) …

The role of platelet-derived growth factor receptor in early brain injury following subarachnoid hemorrhage

C Zhou, G Zhang, X He, X Xia, X Sun, Y Xie - Journal of Stroke and …, 2016 - Elsevier
Objective This study aims to observe encephaledema and cell apoptosis in rats following
subarachnoid hemorrhage (SAH) and to explore the mechanism of platelet-derived growth …

Comparison of brain cell death and inflammatory reaction in three models of intracerebral hemorrhage in adult rats

M Xue, MR Del Bigio - Journal of Stroke and Cerebrovascular Diseases, 2003 - Elsevier
Intracerebral hemorrhage (ICH) is associated with stroke and head trauma. Different
experimental models are used, but it is unclear to what extent the tissue responses are …

Experimental Subarachnoid Hemorrhage Causes Early and Long-Lasting Microarterial Constriction and Microthrombosis: An in-vivo Microscopy Study

B Friedrich, F Müller, S Feiler… - Journal of Cerebral …, 2012 - journals.sagepub.com
Early brain injury (EBI) after subarachnoid hemorrhage (SAH) is characterized by a severe,
cerebral perfusion pressure (CPP)-independent reduction in cerebral blood flow suggesting …

[图书][B] Comparison of different preclinical models of intracerebral hemorrhage

A Manaenko, H Chen, JH Zhang, J Tang - 2011 - Springer
Intracerebral hemorrhage (ICH) is the most devastating type of stroke. It is characterized by
spontaneous bleeding in brain parenchyma and is associated with a high rate of morbidity …

Rosiglitazone attenuates hyperglycemia-enhanced hemorrhagic transformation after transient focal ischemia in rats

FH Zhang, YH Lin, HG Huang, JZ Sun, SQ Wen, M Lou - Neuroscience, 2013 - Elsevier
Hemorrhagic transformation (HT) has been claimed to represent the most feared
complication of treatment with intravenous tissue plasminogen activator (t-PA) therapy. In …

Assessing functional outcomes following intracerebral hemorrhage in rats

R Hartman, T Lekic, H Rojas, J Tang, JH Zhang - Brain research, 2009 - Elsevier
Translational neuroprotective and drug development studies need to be gauged against
well-characterized functional outcomes, including motor, sensory and cognitive domains …

[HTML][HTML] Statins enhance expression of growth factors and activate the PI3K/Akt-mediated signaling pathway after experimental intracerebral hemorrhage

D Yang, Y Han, J Zhang, M Chopp… - World journal of …, 2012 - ncbi.nlm.nih.gov
Previous studies have demonstrates that statins improve neurological outcome and promote
neurovascular recovery after ICH. This study is designed to examine whether simvastatin …