A current need in the neuroscience field is a simple method to monitor autophagic activity in
vivo in neurons. Until very recently, most reports have been based on correlative and static …

Autophagy is a process traditionally known to contribute to cellular cleaning through the
removal of intracellular components in lysosomes. In recent years, intensive scrutiny at the …

Autophagy is an intracellular bulk degradation system that is found ubiquitously in
eukaryotes. Autophagy is responsible for the degradation of most long-lived proteins and …

Autophagy is a lysosomal degradation pathway of eukaryotic cells that is highly conserved
from yeast to mammals. During this process, cooperating protein complexes are recruited in …

Depending on the circumstances, autophagy can prevent, cause or regulate the kinetics of
cell death. Consequently, it is particularly important that experimental strategies to study …

(Macro) Autophagy is a phylogenetically conserved membrane-trafficking process that
functions to deliver cytoplasmic cargoes to lysosomes for digestion. The process is a major …

Autophagy was first discovered by transmission electron microscopy more than 50 years
ago. For decades, electron microscopy was the only way to reliably detect autophagic …

Autophagy involves the isolation and targeting of unwanted cellular components to
lysosomes for their digestion and reuse. Autophagic dysregulation has recently been …

Macroautophagy (hereafter autophagy) plays a crucial role in maintaining cellular
homeostasis by degrading and recycling damaged cellular components (1, 2). In health …

Autophagy is a conserved intracellular catabolic pathway that degrades unnecessary or
dysfunctional cellular components. Components destined for degradation are sequestered …