The ablative role of minimally invasive surgery (MIS) in neuroblastoma (NB) is still
controversial due to the possible CO₂ pneumoperitoneum side-effects on tumor …

Purpose The proto-oncogene MYCN is considered a transcription factor involved in the
regulation of neuroblastoma (NB) cell biology. Since minimally invasive-surgery represents …

Introduction CO 2 pneumoperitoneum can influence the biological behavior of
neuroblastoma (NB). Angiogenesis and genetic features are responsible for malignant …

Peritoneal carcinomatosis of colorectal cancer is common and associated with poor
prognosis, which poses a serious challenge and satisfactory treatments are urgently …

The effects and potential molecular mechanisms underlying carbon dioxide (CO 2)
pneumoperitoneum on gastric cancer cell apoptosis are not fully understood. In this study …

Purpose We evaluated in vitro the role of CO 2-induced oxidative stress on the expression of
proteins involved in cell-cycle regulation of neuroblastoma cells. Methods SH-SY5Y cells …

Background Minimally invasive techniques are increasingly used for biopsy and resection of
neuroblastoma, but the impact on the behavior of spilled tumor cells is unknown. We aimed …

Purpose: It has been reported that CO 2 gas, used to establish a pneumoperitoneum during
laparoscopy, affects the behavior of tumor cells. The proto-oncogenes c-myc and HMGB-1 …

Object: The authors studied the influence of CO 2 pneumoperitoneum on intracellular pH
and signal transduction arising from cancer cell multiplication in laparoscopic tumor …

Hypoxia and acidosis are hallmarks of tumors as well as critical determinants of response to
treatments. In present study, we investigate the extent to which changes in O2/CO2 gas ratio …