Background Estrogen receptor β (ERβ) is a potential tumor-suppressor gene in colorectal
cancer (CRC). This hypothesis is supported by clinical and laboratory observations. Aim In …

We have investigated the presence of oestrogen receptor-related (ERR) mRNA in human
colorectal tumour tissues and adjacent normal mucosa by reverse transcriptase and nested …

Colon cancer incidence and mortality rates are lower in females compared with males, and
numerous epidemiological studies suggest that estrogen replacement therapy (ERT) …

Purpose A large number of studies have suggested an inhibitory role of estrogens against
colorectal cancer (CRC), but persistent controversy exists. CRC characteristics are affected …

Estrogens play important roles in the development and progression of multiple tumor types.
Accumulating evidence points to the significance of estrogen action not only in tumors of …

The role of oestrogen in oncogenesis has been examined extensively, especially in the
context of breast cancer, and receptor modulators are an integral part of targeted treatment …

Colon cancer is the most frequent neoplasia of the intestine. This pathology is the third
highest cause of death from cancer with 430,000 deaths globally per year. Estrogen has …

Estrogen receptor β (ERβ) is the predominant ER in the colorectal epithelium. Compared
with normal colon tissue, ERβ expression is reduced in colorectal cancer. Our hypothesis is …

In recent years, several lines of epidemiologic, clinical and experimental evidences have
been reported showing that estrogen hormones may be involved in malignant colorectal …

Oestrogen receptor β (ERβ) has been suggested to have anti‐proliferative and anti‐tumour
effects in breast and prostate cancer cells, but other studies have indicated its tumour …