Brain-derived neurotrophic factor in Alzheimer's disease: risk, mechanisms, and therapy
JH Song, JT Yu, L Tan - Molecular neurobiology, 2015 - Springer
Brain-derived neurotrophic factor (BDNF) has a neurotrophic support on neuron of central
nervous system (CNS) and is a key molecule in the maintenance of synaptic plasticity and …
nervous system (CNS) and is a key molecule in the maintenance of synaptic plasticity and …
[HTML][HTML] Brain-derived neurotrophic factor in Alzheimer's disease and its pharmaceutical potential
L Gao, Y Zhang, K Sterling, W Song - Translational neurodegeneration, 2022 - Springer
Synaptic abnormalities are a cardinal feature of Alzheimer's disease (AD) that are known to
arise as the disease progresses. A growing body of evidence suggests that pathological …
arise as the disease progresses. A growing body of evidence suggests that pathological …
[图书][B] Neurotrophic factors and Alzheimer's disease: are we focusing on the wrong molecule?
M Fahnestock, D Garzon, RMD Holsinger, B Michalski - 2002 - Springer
Brain derived neurotrophic factor (BDNF) promotes cholinergic neuron function and survival.
In Alzheimer's disease, BDNF mRNA and protein are decreased in basal forebrain …
In Alzheimer's disease, BDNF mRNA and protein are decreased in basal forebrain …
Brain-derived neurotrophic factor and Alzheimer's disease: physiopathology and beyond
BS Diniz, AL Teixeira - Neuromolecular medicine, 2011 - Springer
Brain-derived neurotrophic factor (BDNF) is the most widely distributed neurotrophin in the
central nervous system where it plays several pivotal roles in synaptic plasticity and …
central nervous system where it plays several pivotal roles in synaptic plasticity and …
[HTML][HTML] Decreased serum brain-derived neurotrophic factor (BDNF) levels in patients with Alzheimer's disease (AD): a systematic review and meta-analysis
Findings from previous studies reporting the levels of serum brain-derived neurotrophic
factor (BDNF) in patients with Alzheimer's disease (AD) and individuals with mild cognitive …
factor (BDNF) in patients with Alzheimer's disease (AD) and individuals with mild cognitive …
Decreased brain-derived neurotrophic factor depends on amyloid aggregation state in transgenic mouse models of Alzheimer's disease
Downregulation of brain-derived neurotrophic factor (BDNF) in the cortex occurs early in the
progression of Alzheimer's disease (AD). Since BDNF plays a critical role in neuronal …
progression of Alzheimer's disease (AD). Since BDNF plays a critical role in neuronal …
The expanding role of BDNF: a therapeutic target for Alzheimer's disease?
F Fumagalli, G Racagni, MA Riva - The pharmacogenomics journal, 2006 - nature.com
Finding an effective treatment for chronic neurodegenerative disorders still represents an
unmet goal. There is considerable evidence that such disorders represent a combination of …
unmet goal. There is considerable evidence that such disorders represent a combination of …
[HTML][HTML] Modulation of BDNF cleavage by plasminogen-activator inhibitor-1 contributes to Alzheimer's neuropathology and cognitive deficits
G Gerenu, E Martisova, H Ferrero, M Carracedo… - … et Biophysica Acta (BBA …, 2017 - Elsevier
Brain-derived neurotrophic factor (BDNF) plays pivotal roles in neuronal function. The
cleaved–mature–form of BDNF (mBDNF), predominantly expressed in adult brains, critically …
cleaved–mature–form of BDNF (mBDNF), predominantly expressed in adult brains, critically …
Pro-brain-derived neurotrophic factor is decreased in parietal cortex in Alzheimer's disease
B Michalski, M Fahnestock - Molecular Brain Research, 2003 - Elsevier
Brain-derived neurotrophic factor (BDNF) promotes the function and survival of the major
neuronal types affected in Alzheimer disease, such as hippocampal, cortical and basal …
neuronal types affected in Alzheimer disease, such as hippocampal, cortical and basal …
[HTML][HTML] Brain-derived neurotrophic factor protects against tau-related neurodegeneration of Alzheimer's disease
SS Jiao, LL Shen, C Zhu, XL Bu, YH Liu, CH Liu… - Translational …, 2016 - nature.com
Reduced expression of brain-derived neurotrophic factor (BDNF) has a crucial role in the
pathogenesis of Alzheimer's disease (AD), which is characterized with the formation of …
pathogenesis of Alzheimer's disease (AD), which is characterized with the formation of …