Neurodegenerative pathways in Alzheimer's disease: a review

AK Ramachandran, S Das, A Joseph… - Current …, 2021 - ingentaconnect.com
Alzheimer's disease (AD) is a complex neurodegenerative disease that leads to insidious
deterioration of brain functions and is considered the sixth leading cause of death in the …

Pathophysiological Aspects and Therapeutic Armamentarium of Alzheimer's Disease: Recent Trends and Future Development

BP Dave, YB Shah, KG Maheshwari… - Cellular and Molecular …, 2023 - Springer
Alzheimer's disease (AD) is the primary cause of dementia and is characterized by the death
of brain cells due to the accumulation of insoluble amyloid plaques, hyperphosphorylation of …

[HTML][HTML] Alzheimer's disease: Insights and new prospects in disease pathophysiology, biomarkers and disease-modifying drugs

AR Monteiro, DJ Barbosa, F Remião, R Silva - Biochemical Pharmacology, 2023 - Elsevier
Alzheimer's disease (AD) is one of the most prevalent neurodegenerative diseases that
affect millions of people worldwide, with both prevalence and incidence increasing with age …

Recent update on the Alzheimer's disease progression, diagnosis and treatment approaches

A Malaiya, M Singhai, M Singh, SK Prajapati… - Current Drug …, 2022 - ingentaconnect.com
Alzheimer's disease (AD) is a multifactorial, progressive, neurodegenerative disorder,
manifested by the loss of memory and cognitive abilities, behavioral disturbance and …

A critical analysis of new molecular targets and strategies for drug developments in Alzheimer's disease

DK Lahiri, MR Farlow, K Sambamurti… - Current drug …, 2003 - ingentaconnect.com
Alzheimer's disease (AD), a progressive, degenerative disorder of the brain, is believed to
be the most common cause of dementia amongst the elderly. AD is characterized by the …

Current concepts of neurodegenerative mechanisms in Alzheimer's disease

KB Magalingam, A Radhakrishnan… - BioMed research …, 2018 - Wiley Online Library
Neurodegenerative diseases are hereditary or sporadic conditions that result in the
progressive loss of the structure and function of neurons as well as neuronal death …

Current and emerging therapies for Alzheimer's disease

HB Nygaard - Clinical therapeutics, 2013 - Elsevier
Alzheimer's disease (AD) is a devastating neurodegenerative disorder, with a rapidly
increasing worldwide prevalence. Although no cure for AD has yet been found, substantial …

Emerging targets in neurodegeneration: new opportunities for Alzheimer's disease treatment?

A Rampa, S Gobbi, F Belluti… - Current Topics in Medicinal …, 2013 - ingentaconnect.com
Alzheimer's disease (AD) is a progressive neurodegenerative disorder of the brain
associated with memory impairment, progressive cognitive decline and changes in …

Therapeutic opportunities in Alzheimer disease: one for all or all for one?

MW Marlatt, KM Webber, PI Moreira… - Current medicinal …, 2005 - ingentaconnect.com
In recent years, Alzheimer disease (AD) has received great attention as an incurable and
fatal disease that threatens the lives of aging individuals. Debates regarding areas of …

Concepts for the treatment of Alzheimer's disease: molecular mechanisms and clinical application

C Pietrzik, C Behl - International journal of experimental …, 2005 - Wiley Online Library
To date, various strategies have been developed in order to prevent or to slow down the
progression of Alzheimer's disease (AD). Despite the medical need for an effective …