Acute respiratory distress syndrome, the critical care paradigm: what we learned and what we forgot

L Gattinoni, E Carlesso, F Valenza… - Current opinion in …, 2004 - journals.lww.com
In the last several years, we definitely learned that the acute respiratory distress syndrome
lung is small, nonhomogeneous, and that mechanical ventilation in this baby lung may …

Is mechanical ventilation a cure for ARDS?

L Gattinoni, M Quintel - Intensive Care Medicine, 2016 - Springer
In general, medical treatment intending to cure a syndrome like the acute respiratory distress
syndrome (ARDS) should treat the etiology, the pathophysiology, and the symptoms. The …

The" baby lung" became an adult

L Gattinoni, JJ Marini, A Pesenti, M Quintel… - Intensive care …, 2016 - Springer
The baby lung was originally defined as the fraction of lung parenchyma that, in acute
respiratory distress syndrome (ARDS), still maintains normal inflation. Its size obviously …

Acute lung injury: pathophysiology, assessment and current therapy

J Hammer - Paediatric respiratory reviews, 2001 - Elsevier
Acute respiratory distress syndrome (ARDS) is a clinically defined entity describing the
severity of diffuse alveolar injury caused by direct or indirect injury to the lung …

The concept of “baby lung”

L Gattinoni, A Pesenti - Applied Physiology in Intensive Care Medicine 1 …, 2012 - Springer
Background: The “baby lung” concept originated as an offspring of computed tomography
examinations which showed in most patients with acute lung injury/acute respiratory distress …

Mechanical ventilation in acute respiratory distress syndrome

YM Wang, YH Tao - Zhongguo Dang dai er ke za zhi= Chinese …, 2013 - europepmc.org
The goal of mechanically ventilating patients with acute respiratory distress syndrome
(ARDS) is to ensure adequate oxygenation and minimal ventilator-associated lung injury …

Mechanical ventilation in children with acute respiratory distress syndrome: a huge gap between what we know and our practice!

JP Piva, PCR Garcia, H Fiori - Pediatric Critical Care Medicine, 2013 - journals.lww.com
The acute respiratory distress syndrome (ARDS) mor-tality decreased dramatically in the last
35 years without any specific treatment or new drug. In this period, we learned that …

Acute respiratory distress syndrome in children

F Beaufils, JC Mercier, C Farnoux… - Current Opinion in …, 1997 - journals.lww.com
The adult (acute) respiratory distress syndrome is a significant cause of morbidity in children.
The mortality rates remain elevated, greater than 50%, and even greater than 80% in …

How to ventilate patients with acute lung injury and acute respiratory distress syndrome

L Gattinoni, P Caironi, E Carlesso - Current opinion in critical care, 2005 - journals.lww.com
Gentle lung ventilation must be standard practice. Because stress and strain are the triggers
of ventilator-induced lung injury, their clinical equivalents should be measured …

New strategies in mechanical ventilation for acute lung injury

H Burchardi - European Respiratory Journal, 1996 - Eur Respiratory Soc
In the fluid-filled lungs of early adult respiratory distress syndrome (ARDS) the dependent
parts are compressed and atelectatic; whereas, the nondependent areas remain aerated …