We have previously shown that Toll-like receptor (TLR) agonists contribute to the control of
viral infection by augmenting virus-specific CD8+ T-cell responses. It is also well established …

Early events during retroviral infection play a critical role in determining the course of
infection and pathogenesis, but the mechanisms that regulate this phase of infection are …

Toll-like receptors (TLRs) comprise a class of highly conserved molecules that recognize
pathogen-associated molecular patterns and play a vital role in host defense against …

Toll-like receptors (TLRs) are critical components of innate immunity and function as rapid
pathogen sensors. TLR4 is expressed on CD4+ T cells as well, the functional significance of …

Background Toll-like receptors (TLRs) play a fundamental role in innate immunity through
their capacity to recognize pathogen-associated molecular patterns. Also, TLRs that are …

Toll-like receptors recognize pathogen-associated molecular patterns, activate innate
immunity, and consequently modulate adaptive immunity in response to infections. TLRs are …

Background Pathogen recognition drives host defense towards viral infections. Specific
groups rather than single members of the protein family of pattern recognition receptors …

Toll-like receptors (TLRs) play a crucial role in activation of innate immunity, which is
essential for inducing effective adaptive immune responses. Our previous studies have …

The activation of TLR7 signaling in T cells accelerates antigen-specific responses. Such
responses play an essential role in eliminating viral infections and can be anti-tumorigenic …

The development of vaccines that can enhance immunity to viral pathogens is an important
goal. However, the innate molecular pathways that regulate the strength and quality of the …