TLR ligand induced IL-6 counter-regulates the anti-viral CD8+ T cell response during an acute retrovirus infection
W Wu, KK Dietze, K Gibbert, KS Lang, M Trilling… - Scientific reports, 2015 - nature.com
We have previously shown that Toll-like receptor (TLR) agonists contribute to the control of
viral infection by augmenting virus-specific CD8+ T-cell responses. It is also well established …
viral infection by augmenting virus-specific CD8+ T-cell responses. It is also well established …
Toll-like receptor 7 inhibits early acute retroviral infection through rapid lymphocyte responses
EP Browne - Journal of virology, 2013 - Am Soc Microbiol
Early events during retroviral infection play a critical role in determining the course of
infection and pathogenesis, but the mechanisms that regulate this phase of infection are …
infection and pathogenesis, but the mechanisms that regulate this phase of infection are …
Contribution of T-and B-cell intrinsic toll-like receptors to the adaptive immune response in viral infectious diseases
E Zhang, Z Ma, M Lu - Cellular and Molecular Life Sciences, 2022 - Springer
Toll-like receptors (TLRs) comprise a class of highly conserved molecules that recognize
pathogen-associated molecular patterns and play a vital role in host defense against …
pathogen-associated molecular patterns and play a vital role in host defense against …
Toll-like receptor 4 signaling in T cells promotes autoimmune inflammation
JM Reynolds, GJ Martinez… - Proceedings of the …, 2012 - National Acad Sciences
Toll-like receptors (TLRs) are critical components of innate immunity and function as rapid
pathogen sensors. TLR4 is expressed on CD4+ T cells as well, the functional significance of …
pathogen sensors. TLR4 is expressed on CD4+ T cells as well, the functional significance of …
Expression and function of TLR2 on CD4 versus CD8 T cells
SM Lee, YD Joo, SK Seo - Immune network, 2009 - synapse.koreamed.org
Background Toll-like receptors (TLRs) play a fundamental role in innate immunity through
their capacity to recognize pathogen-associated molecular patterns. Also, TLRs that are …
their capacity to recognize pathogen-associated molecular patterns. Also, TLRs that are …
Cutting edge: TLR2 directly triggers Th1 effector functions
T Imanishi, H Hara, S Suzuki, N Suzuki… - The Journal of …, 2007 - journals.aai.org
Toll-like receptors recognize pathogen-associated molecular patterns, activate innate
immunity, and consequently modulate adaptive immunity in response to infections. TLRs are …
immunity, and consequently modulate adaptive immunity in response to infections. TLRs are …
Friend retrovirus drives cytotoxic effectors through Toll-like receptor 3
K Gibbert, S Francois, AM Sigmund, MS Harper… - Retrovirology, 2014 - Springer
Background Pathogen recognition drives host defense towards viral infections. Specific
groups rather than single members of the protein family of pattern recognition receptors …
groups rather than single members of the protein family of pattern recognition receptors …
Pre-Activation of Toll-Like Receptor 2 Enhances CD8+ T-Cell Responses and Accelerates Hepatitis B Virus Clearance in the Mouse Models
Y Lin, X Huang, J Wu, J Liu, M Chen, Z Ma… - Frontiers in …, 2018 - frontiersin.org
Toll-like receptors (TLRs) play a crucial role in activation of innate immunity, which is
essential for inducing effective adaptive immune responses. Our previous studies have …
essential for inducing effective adaptive immune responses. Our previous studies have …
Toll-like receptor 7 activation enhances CD8+ T cell effector functions by promoting cellular glycolysis
The activation of TLR7 signaling in T cells accelerates antigen-specific responses. Such
responses play an essential role in eliminating viral infections and can be anti-tumorigenic …
responses play an essential role in eliminating viral infections and can be anti-tumorigenic …
Toll-like receptor 7 controls the anti-retroviral germinal center response
EP Browne - PLoS pathogens, 2011 - journals.plos.org
The development of vaccines that can enhance immunity to viral pathogens is an important
goal. However, the innate molecular pathways that regulate the strength and quality of the …
goal. However, the innate molecular pathways that regulate the strength and quality of the …