Cryptococcus neoformans: morphogenesis, infection, and evolution

X Lin - Infection, Genetics and Evolution, 2009 - Elsevier
Cryptococcus neoformans is the major causative agent of fungal meningoencephalitis in
both immunocompromised and immunocompetent individuals. During infection, this fungus …

The Biology of the Cryptococcus neoformans Species Complex

X Lin, J Heitman - Annu. Rev. Microbiol., 2006 - annualreviews.org
Cryptococcus neoformans is a major cause of fungal meningoencephalitis in
immunocompromised patients. Despite recent advances in the genetics and molecular …

Profiling a killer, the development of Cryptococcus neoformans

L Kozubowski, J Heitman - FEMS microbiology reviews, 2012 - academic.oup.com
The ability of fungi to transition between unicellular and multicellular growth has a profound
impact on our health and the economy. Many important fungal pathogens of humans …

The interplay of phenotype and genotype in Cryptococcus neoformans disease

S Altamirano, KM Jackson, K Nielsen - Bioscience Reports, 2020 - portlandpress.com
Cryptococcus neoformans is an opportunistic fungal pathogen that causes life-threatening
meningitis primarily in immunocompromised individuals. In order to survive and proliferate …

Cryptococcus neoformans: historical curiosity to modern pathogen

D Srikanta, FH Santiago‐Tirado, TL Doering - Yeast, 2014 - Wiley Online Library
The importance of the Basidiomycete Cryptococcus neoformans to human health has
stimulated its development as an experimental model for both basic physiology and …

Comparative Genomics of Serial Isolates of Cryptococcus neoformans Reveals Gene Associated With Carbon Utilization and Virulence

KL Ormerod, CA Morrow, EWL Chow… - G3: Genes …, 2013 - academic.oup.com
The opportunistic fungal pathogen Cryptococcus neoformans is a leading cause of mortality
among the human immunodeficiency virus/acquired immunodeficiency syndrome …

[HTML][HTML] The origin and maintenance of virulence for the human pathogenic fungus Cryptococcus neoformans

JN Steenbergen, A Casadevall - Microbes and infection, 2003 - Elsevier
The origin of virulence in environmental fungi that have no requirement for animal hosts in
their life cycle is enigmatic. Cryptococcus neoformans is a human pathogenic fungus with …

Survival Defects of Cryptococcus neoformans Mutants Exposed to Human Cerebrospinal Fluid Result in Attenuated Virulence in an Experimental Model of Meningitis

A Lee, DL Toffaletti, J Tenor, EJ Soderblom… - Infection and …, 2010 - Am Soc Microbiol
Cryptococcus neoformans is a fungal pathogen that encounters various microenvironments
during growth in the mammalian host, including intracellular vacuoles, blood, and …

Microbe Profile: Cryptococcus neoformans species complex

YS Bahn, S Sun, J Heitman, X Lin - Microbiology, 2020 - microbiologyresearch.org
Cryptococcus neoformans is a lethal fungus disguised in a polysaccharide coat. It can
remain dormant in the host for decades prior to reactivation, causing systemic …

Microevolution of Serial Clinical Isolates of Cryptococcus neoformans var. grubii and C. gattii

Y Chen, RA Farrer, C Giamberardino, S Sakthikumar… - MBio, 2017 - Am Soc Microbiol
The pathogenic species of Cryptococcus are a major cause of mortality owing to severe
infections in immunocompromised as well as immunocompetent individuals. Although …