Obesity represents the most prevalent nutritional problem worldwide which in the long run
predisposes to development of diabetes mellitus, hypertension, endometrial carcinoma …

Energy homeostasis is controlled by a complex neuroendocrine system consisting of
peripheral signals like leptin and central signals, in particular, neuropeptides. Several …

Obesity, a condition already at epidemic proportions in the developed world, is largely
attributable to an indulgent lifestyle. Biologically we feel hunger more acutely than feeling; …

Obesity is important in the aetiology of type 2 diabetes, and presents a major barrier to its
successful prevention and management. Obesity develops when energy intake exceeds …

The discovery of the adiposity signal leptin a decade ago revolutionised our understanding
of the hypothalamic mechanisms underpinning the central control of ingestive behaviour …

This review focuses on the expression, content, and release of neuropeptides and on their
role in the development of obesity in animal models with single-gene mutations. The …

Neuropeptides released by hypothalamic neurons play a major role in the regulation of
feeding, acting both within the hypothalamus, and at other appetite regulating centres …

It has been recognized for some time that a number of different neuropeptides exert powerful
effects on food intake. During the last few years, the neurocircuitry within which these …

The worldwide increase in the incidence of obesity is a consequence of a positive energy
balance, with energy intake exceeding expenditure. The signalling systems that underlie …

Neuropeptides are essential for the regulation of appetite and body weight within the
hypothalamus. The understanding of the neuropeptide regulation of energy homeostasis …