Cancer cells are different from normal cells in their metabolic properties. Normal cells mostly
rely on mitochondrial oxidative phosphorylation to produce energy. In contrast, cancer cells …

Highlights•Tumor cells increase their metabolic rates as well as glucose uptake to maintain
amplified proliferation,•Consequently, tumor cells switch from mitochondrial oxidative …

Since the first theorization of the Warburg effect as a metabolic characteristic of cancer, a
great deal of progress has been made in the understanding of molecular details underlying …

Tumor cells rely mainly on glycolysis for energy production even in the presence of sufficient
oxygen, a phenomenon termed the Warburg effect, which is the most outstanding …

Increased aerobic glycolysis in cancer, a phenomenon known as the Warburg effect, has
been observed in various tumor cells and represents a major biochemical alteration …

Cancer metabolism has emerged as an important area of research in recent years.
Elucidation of the metabolic differences between cancer and normal cells and the …

Most cancer cells exhibit increased glycolysis and use this metabolic pathway for generation
of ATP as a main source of their energy supply. This phenomenon is known as the Warburg …

Reprogramming of cellular metabolism is a hallmark of cancers. Cancer cells more readily
use glycolysis, an inefficient metabolic pathway for energy metabolism, even when sufficient …

Described decades ago, the Warburg effect of aerobic glycolysis is a key metabolic hallmark
of cancer, yet its significance remains unclear. In this Essay, we re-examine the Warburg …

Although survival outcomes of cancer patients have been improved dramatically via
conventional chemotherapy and targeted therapy over the last decades, there are still some …