Cancer cells rewire their metabolism to promote growth, survival, proliferation, and long-term
maintenance. The common feature of this altered metabolism is the increased glucose …

Introduction One of the most distinctive hallmarks of cancer cells is increased glucose
consumption for aerobic glycolysis, which is called the Warburg effect. In recent decades …

Metabolic reprogramming is one of the critical features in cancer. Tumor cells preferentially
utilize glycolysis instead of oxidative phosphorylation in the presence of oxygen, namely …

Most solid tumor cells adapt to their heterogeneous microenvironment by depending largely
on aerobic glycolysis for energy production, a phenomenon called the Warburg effect, which …

The Warburg effect was first described by Otto Warburg in the 1920s and describes the
preferential conversion of glucose to lactate as opposed to its metabolism through the citric …

The Warburg effect in tumor cells involves the uptake of high levels of glucose, enhanced
glycolysis, and the metabolism of pyruvate to lactic acid rather than oxidative phos …

Cancer cells exhibit metabolic reprogramming and bioenergetic alteration, utilizing glucose
fermentation for energy production, known as the Warburg effect. However, there are a lack …

Warburg and coworkers' observation of altered glucose metabolism in tumours has been
neglected for several decades, which, in part, was because of an initial misinterpretation of …

Several decades ago, Otto Warburg discovered that cancer cells produce energy
predominantly by glycolysis; a phenomenon now termed “Warburg effect”. Warburg linked …

Aerobic glycolysis is an emerging hallmark of many human cancers, as cancer cells are
defined as a “metabolically abnormal system”. Carbohydrates are metabolically …