Revisited metabolic control and reprogramming cancers by means of the warburg effect in tumor cells

A Fukushi, HD Kim, YC Chang, CH Kim - International journal of …, 2022 - mdpi.com
Aerobic glycolysis is an emerging hallmark of many human cancers, as cancer cells are
defined as a “metabolically abnormal system”. Carbohydrates are metabolically …

The metabolic landscape of lung cancer: new insights in a disturbed glucose metabolism

K Vanhove, GJ Graulus, L Mesotten, M Thomeer… - Frontiers in …, 2019 - frontiersin.org
Metabolism encompasses the biochemical processes that allow healthy cells to keep
energy, redox balance and building blocks required for cell development, survival, and …

Biochemical origin of the Warburg effect in light of 15 years of research experience: a novel evidence-based view (An Expert Opinion Article)

SM El Sayed - OncoTargets and Therapy, 2023 - Taylor & Francis
Cancer cells strongly upregulate glucose uptake and glycolysis to produce vital
biomolecules for cancer cell survival, proliferation, and metastasis as ATP, lipids, proteins …

Dysregulated glycolysis as an oncogenic event

T Mikawa, ME LLeonart, A Takaori-Kondo… - Cellular and Molecular …, 2015 - Springer
Enhanced glycolysis in cancer, called the Warburg effect, is a well-known feature of cancer
metabolism. Recent advances revealed that the Warburg effect is coupled to many other …

Cellular life span and the Warburg effect

H Kondoh - Experimental cell research, 2008 - Elsevier
Enhanced glycolysis is observed in most of cancerous cells and tissues, called as the
Warburg effect. Recent advance in senescent biology implicates that the metabolic shift to …

L'effet Warburg

J Razungles, V Cavaillès, S Jalaguier… - Med Sci …, 2013 - medecinesciences.org
> Le métabolisme des cellules cancéreuses décrit par Otto Warburg dans les années 1930
est devenu une marque spécifique associée au cancer, appelée «effet Warburg». Les …

[HTML][HTML] Alterations in cancer cell metabolism: the Warburg effect and metabolic adaptation

Y Asgari, Z Zabihinpour, A Salehzadeh-Yazdi… - Genomics, 2015 - Elsevier
The Warburg effect means higher glucose uptake of cancer cells compared to normal
tissues, whereas a smaller fraction of this glucose is employed for oxidative phosphorylation …

Crucial players in glycolysis: cancer progress

Z Abbaszadeh, S Çeşmeli, ÇB Avcı - Gene, 2020 - Elsevier
Cancer is the second most important cause of death and new therapy modalities continue to
be developed and evolved. Cancer cells' metabolism is far different from the normal, healthy …

[HTML][HTML] Metabolic interplay between glycolysis and mitochondrial oxidation: The reverse Warburg effect and its therapeutic implication

M Lee, JH Yoon - World journal of biological chemistry, 2015 - ncbi.nlm.nih.gov
Aerobic glycolysis, ie., the Warburg effect, may contribute to the aggressive phenotype of
hepatocellular carcinoma. However, increasing evidence highlights the limitations of the …

Tumor cells and cancer-associated fibroblasts: an updated metabolic perspective

G Gentric, F Mechta-Grigoriou - Cancers, 2021 - mdpi.com
Simple Summary Tumors are a complex ecosystem including not only cancer cells, but also
many distinct cell types of the tumor micro-environment. While the Warburg effect assessing …