The success of 131I ablation in thyroid cancer patients is significantly reduced after a diagnostic activity of 40 MBq 131I

FA Verburg, RBT Verkooijen… - Nuklearmedizin …, 2009 - thieme-connect.com
Objective: Dosimetry studies have shown that activities of 131 I as small as 10-20 MBq may
cause a stunning effect. A result of this stunning effect may be a lower success rate of the …

The success rate of I-131 ablation in differentiated thyroid cancer: comparison of uptake-related and fixed-dose strategies

RBT Verkooijen, FA Verburg… - European journal of …, 2008 - academic.oup.com
Introduction The aim of the study was to compare the success rate of an uptake-related
ablation protocol in which the dose depends on an I-131 24-h neck uptake measurement …

Decreased uptake after fractionated ablative doses of iodine-131

HS Wu, HH Hseu, WY Lin, SJ Wang, YC Liu - European Journal of …, 2005 - Springer
Purpose In an attempt to obviate the necessity for hospitalisation, the ablative dose of 131 I
in the treatment of thyroid cancer is divided into two or three fractions at weekly intervals in …

The absorbed dose to the blood is a better predictor of ablation success than the administered 131I activity in thyroid cancer patients

FA Verburg, M Lassmann, U Mäder, M Luster… - European journal of …, 2011 - Springer
Purpose The residence time of 131 I in the blood is likely to be a measure of the amount of
131 I that is available for uptake by thyroid remnant tissue and thus the radiation absorbed …

The management of differentiated thyroid cancer using 123I for imaging to assess the need for 131I therapy

N Ali, C Sebastian, RR Foley, I Murray… - Nuclear medicine …, 2006 - journals.lww.com
Background Follow-up of 131 I whole-body scanning after 131 I ablation is associated with
potential stunning. Previous studies have suggested that, for scanning, 123 I is more …

No Adverse Affect in Clinical Outcome Using Low Preablation Diagnostic 131I Activity in Differentiated Thyroid Cancer: Refuting Thyroid-Stunning Effect

BK Yap, B Murby - The Journal of Clinical Endocrinology & …, 2014 - academic.oup.com
Context: Published studies of thyroid stunning due to preablation 131I scanning in the
treatment of differentiated thyroid cancer after thyroidectomy had shown inconsistent clinical …

Efficacy of I131 ablation therapy using different doses as determined by postoperative thyroid scan uptake in patients with differentiated thyroid cancer

J Zidan, E Hefer, G Iosilevski, K Drumea… - International Journal of …, 2004 - Elsevier
PURPOSE: The optimal dose of I131 for ablation of functioning residual thyroid tissue after
surgery is controversial. The current study was conducted to determine the optimal dose of …

The outcome of I-131 ablation therapy for intermediate and high-risk differentiated thyroid cancer using a strict definition of successful ablation

K Watanabe, M Uchiyama, K Fukuda - Japanese Journal of Radiology, 2017 - Springer
Purpose This article examines the outcome of radioactive iodine ablation therapy for thyroid
cancer in high-risk patients and investigates background factors influencing ablation failure …

Are there disadvantages in administering 131I ablation therapy in patients with differentiated thyroid carcinoma without a preablative diagnostic 131I whole‐body …

M Salvatori, G Perotti, V Rufini… - Clinical …, 2004 - Wiley Online Library
Summary objective To evaluate the risk of performing inappropriate 131I ablative therapies
for thyroid carcinoma in patients lacking thyroid remnants or metastases, using a strategy of …

What is the role of 1100 MBq (< 30 mCi) radioiodine 131I in the treatment of patients with differentiated thyroid cancer?

M Van Wyngaarden, IR McDougall - Nuclear medicine …, 1996 - journals.lww.com
Based on pre-therapy whole-body 131 I scintiscans showing only residual thyroid, 64
patients with differentiated thyroid cancer were treated with 1100 MBq (< 30 mCi) 131 I as …