The molecular basis of membrane water-permeability remained elusive until the recent
discovery of the aquaporin water-channel proteins. The fundamental importance of these …

Recent discovery of a family of water-specific membrane channel proteins, the aquaporins,
has provided new insights into the molecular basis of membrane water permeability. Eleven …

Our understanding of the movement of water through cell membranes has been greatly
advanced by the discovery of a family of water-specific, membrane-channel proteins—the …

The recent discovery of aquaporins, a family of highly conserved water channel proteins,
which are expressed in both eukaryotes and prokaryotes, has provoked a re-evaluation of …

The long-standing biophysical question of how water crosses plasma membranes has been
answered by the recent discovery of the aquaporins. Identification of this large family of …

Following the discovery of the aquaporin-1 water channel in 1991, molecular techniques
have been developed to examine the roles of renal aquaporins-1,-2,-3, and-4 in disorders of …

In mammalian cells water slowly passes across cell membranes driven by osmotic forces.
However, the speed of this process is insufficient for sustained and rapid water fluxes …

Discovery of aquaporin water channel proteins has provided insight into the molecular
mechanism of membrane water permeability. The distribution of known mammalian …

The discovery of aquaporins by Agre and co-workers provided an answer to the long-
standing biophysical question of how water can pass cell membranes. The identification and …

Over the past decade, significant advances have been made in understanding how water
moves in to and out of cells. Investigators have used molecular and structural biological …