In essential hypertension, ventricular function is determined primarily by the degree of
hypertrophy (myocardial factor) and by the organic complications in the coronary artery …

Since left ventricular hypertrophy is considered to be a precursor of later hypertensive heart
failure, a treatment that can prevent or even reverse myocardial hypertrophy is a highly …

Pharmacotherapeutical means of reversing cardiac hypertrophy (prazosin, clonidine and
nifedipine) were analysed in concentrically, as well as eccentrically, hypertrophied left …

The criteria of the degree of hypertrophy and dilatation are defined. On this basis, functional
and therapeutical regimen of regression of cardiac hypertrophy (prazosin, clonidine …

Coronary reserve in man is reduced in concentric hypertensive hypertrophy. In 65-week-old
spontaneously hypertensive rats (SHR) we found similar changes; in perfusion studies on …

Coronary hemodynamics (blood flow, coronary reserve, myocardial oxygen consumption)
were analyzed in both experimental and clinical hypertension. Significantly reduced …

This study analyzes and compares systemic and coronary hemodynamics in patients with
essential hypertension in relation to hypertrophic heart disease of nonhypertensive origin …

Cardiac hypertrophy in essential hypertension is documented to be an independent risk
factor for congestive heart failure, coronary heart disease and cardiac sudden death …

Regression of cardiac hypertrophy has been proven to occur in experimental animals
following some types of antihypertensive therapy. However, no direct and necessary …

Biochemical (myocardial DNA, RNA, and hydroxyproline) and humoral (plasma [PRA] and
kidney [KRA] renin activity) factors were determined in spontaneously hypertensive rats …