Abstract Development of an effective vaccine to prevent Staphylococcus aureus diseasein
humans continues to be a major challenge for the research community. There have been …

Staphylococcus aureus, a prevalent human pathogen and a leading cause of hospital-
acquired infections, is increasingly evolving antibiotic-resistant strains, increasing mortality …

Bacterial vaccines have made dramatic impacts upon morbidity and mortality caused by a
number of common pathogens, but a vaccine to prevent Staphylococcus aureus infections …

INTRODUCTION Nearly three quarters of a century after the introduction of the potent anti-
staphylococcal drug penicillin, Staphylococcus aureus remains a significant bacterial cause …

Staphylococcus aureus is one of the most important human pathogens worldwide. Its high
antibiotic resistance profile reinforces the need for new interventions like vaccines in …

Developing a universal vaccine for S. aureus is a top priority but to date we have only had
failures in human clinical trials. Given the plethora of bacterial virulence factors, broad range …

In this review, we examine the current status of S taphylococcus aureus vaccine
development and the prospects for future vaccines. Examination of the clinical trials to date …

High attack rates and the ability of Staphylococcus aureus to develop resistance to all
antibiotics in medical practice heightens the urgency for vaccine development. S. aureus …

Staphylococcus aureus is a highly successful bacterial pathogen owing to its abundance of
cell surface and secreted virulence factors. It is estimated that 30% of the population is …

Staphylococcus aureus is a major cause of life-threatening infections such as bacteremia
and endocarditis. Unfortunately, many strains of this bacterial species have become …