Acute asthma presentations account for 2 million emergency department visits annually in
the United States. The causes for these presentations range from undertreated or …

Asthma is a common and potentially life threatening childhood condition. Asthma involves
not only chronic airway remodeling, but may also include frequent exacerbations resulting …

Acute severe paediatric asthma remains a serious and debilitating disease throughout the
world. The incidence and mortality from asthma continue to increase. Early, effective and …

Background In acute severe asthma, treatment must be initiated early to reverse the
pathophysiology that may render airways less responsive to bronchodilation. The addition of …

OBJECTIVE: To characterize the clinical course, therapies, and outcomes of children with
fatal and near-fatal asthma admitted to pediatric intensive care units (PICUs). STUDY …

The heterogeneity of asthma is illustrated by the significantly different features of pediatric
asthma compared to adult asthma. One phenotype of severe asthma in pediatrics includes …

The prevalence of patients with acute severe asthma appears to be increasing in many
countries. In the present review, we summarize data in the literature relating to the …

Severe asthma accounts for only a small proportion of the children with asthma but a
disproportionately high amount of resource utilization and morbidity. It is a heterogeneous …

Abstract Purpose of Review The aim of this study is to characterize, diagnose, evaluate, and
treat severe childhood asthma. Recent Findings Understanding the occurrence of the …

The initial definitions of severe/refractory asthma were published in the European
Respiratory Journal and the American Journal of Respiratory and Critical Care Medicine in …