Capsaicin is the pungent ingredient of chili peppers and is approved as a topical treatment
of neuropathic pain. The analgesia lasts for several months after a single treatment …

Capsaicin is the active ingredient of chili peppers and gives them the characteristic pungent
flavor. Understanding the actions of capsaicin led to the discovery of its receptor, transient …

Capsaicin has long been used as a traditional medicine to treat pain and, recently, its
mechanism of analgesic action has been discovered. This review article documents the …

A large number of pharmacological studies have used capsaicin as a tool to activate many
physiological systems, with an emphasis on pain research but also including functions such …

The TRPV1 receptor is known to play a role in nociceptive transmission in multiple organ
systems, usually in response to the pain of inflammation. TRPV1 antagonism has so far …

Capsaicin, the pungent ingredient in chili peppers, produces intense burning pain in
humans. Capsaicin selectively activates the transient receptor potential vanilloid 1 (TRPV1) …

Neuropathic pain is a frequent and disabling condition with diverse underlying etiologies
and is often difficult to treat. Systemic drug treatment is often limited in efficacy. Furthermore …

Abstract Purpose of Review Capsaicin is a natural substance used to treat neuropathic pain
because of its ability to be used in a more direct form on patients and efficiently treat their …

In this review, we discuss the importance of capsaicin to the current understanding of
neuronal modulation of pain and explore the mechanisms of capsaicin-induced pain. We …

Capsaicin, the most pungent ingredient in red peppers, has been used for centuries to
remedy pain. Recently, its role has come under reinvestigation due to evidence that the drug …