Transport and interactions of nanoparticles in the kidneys

B Du, M Yu, J Zheng - Nature Reviews Materials, 2018 - nature.com
Kidneys are a major organ for blood filtration and waste elimination and thus play a key role
in the transport and clearance of nanoparticles in vivo. The interactions of nanoparticles with …

Nanomedicines for renal management: from imaging to treatment

D Jiang, ZT Rosenkrans, D Ni, J Lin… - Accounts of chemical …, 2020 - ACS Publications
Conspectus Nanomedicine has benefited from recent advances in chemistry and biomedical
engineering to produce nanoscale materials as theranostic agents. Well-designed …

Improving kidney targeting: The influence of nanoparticle physicochemical properties on kidney interactions

Y Huang, J Wang, K Jiang, EJ Chung - Journal of Controlled Release, 2021 - Elsevier
Kidney-targeted nanoparticles have become of recent interest due to their potential to
deliver drugs directly to diseased tissue, decrease off-target adverse effects, and increase …

[PDF][PDF] Imaging nano-bio interactions in the kidney: toward a better understanding of nanoparticle clearance

J Wang, G Liu - Angew. Chem., Int. Ed, 2018 - academia.edu
Inorganic nanoparticle (NP) based imaging contrast agents with tuneable shape, size, and
surface chemistry have immense potential in both basic research and clinical settings …

[HTML][HTML] Nanomedicines for kidney diseases

RM Williams, EA Jaimes, DA Heller - Kidney international, 2016 - Elsevier
Nanomedicines have been the subject of great interest for the treatment, diagnosis, and
research of disease; however, few specifically address kidney disorders. Nanotechnology …

Nanomedicines for renal disease: current status and future applications

N Kamaly, JC He, DA Ausiello… - Nature Reviews …, 2016 - nature.com
Abstract Treatment and management of kidney disease currently presents an enormous
global burden, and the application of nanotechnology principles to renal disease therapy …

Atypical renal clearance of nanoparticles larger than the kidney filtration threshold

CF Adhipandito, SH Cheung, YH Lin… - International journal of …, 2021 - mdpi.com
In recent years, several publications reported that nanoparticles larger than the kidney
filtration threshold were found intact in the urine after being injected into laboratory mice …

Short-and long-term tracking of anionic ultrasmall nanoparticles in kidney

X Liang, H Wang, Y Zhu, R Zhang, VC Cogger, X Liu… - ACS …, 2016 - ACS Publications
While biodistribution of nanoparticles (NPs) has been widely studied at the organ level,
relatively little is known about their disposition in organs at the cellular level, especially after …

Clearance properties of nano-sized particles and molecules as imaging agents: considerations and caveats

M Longmire, PL Choyke, H Kobayashi - Nanomedicine, 2008 - Taylor & Francis
Nanoparticles possess enormous potential as diagnostic imaging agents and hold promise
for the development of multimodality agents with both imaging and therapeutic capabilities …

Targeting therapeutics to the glomerulus with nanoparticles

JE Zuckerman, ME Davis - Advances in chronic kidney disease, 2013 - Elsevier
Nanoparticles are an enabling technology for the creation of tissue-/cell-specific
therapeutics that have been investigated extensively as targeted therapeutics for cancer …