[HTML][HTML] Molecular basis and targeted therapy in thyroid cancer: Progress and opportunities

L Zhang, Q Feng, J Wang, Z Tan, Q Li, M Ge - Biochimica et Biophysica …, 2023 - Elsevier
Thyroid cancer (TC) is the most prevalent endocrine malignant tumor. Surgery,
chemotherapy, radiotherapy, and radioactive iodine (RAI) therapy are the standard TC …

High grade differentiated follicular cell-derived thyroid carcinoma versus poorly differentiated thyroid carcinoma: a clinicopathologic analysis of 41 cases

LDR Thompson - Endocrine Pathology, 2023 - Springer
Criteria overlap for separating between malignant follicular epithelial cell-derived thyroid
gland neoplasms with high grade features of increased mitoses and tumor necrosis but …

[HTML][HTML] State of the art in the current management and future directions of targeted therapy for differentiated thyroid cancer

H Silaghi, V Lozovanu, CE Georgescu, C Pop… - International Journal of …, 2022 - mdpi.com
Two-thirds of differentiated thyroid cancer (DTC) patients with distant metastases would be
classified as radioactive iodine-refractory (RAIR-DTC), evolving into a poor outcome. Recent …

An examination of recently revised differentiated thyroid cancer guidelines

BS Miller, GM Doherty - Current opinion in oncology, 2011 - journals.lww.com
Guidelines for the management of differentiated thyroid cancer should continue to reflect
minor regional variations in thyroid cancer treatment based on factors unique to that …

Aggressive differentiated thyroid cancer

N Janjua, VB Wreesmann - European Journal of Surgical Oncology, 2018 - Elsevier
Differentiated thyroid cancer is characteristically associated with an innocuous clinical
course, but a minority of cases may manifest surprisingly aggressive behaviour. Such …

Clinical impact of molecular analysis on thyroid cancer management

VB Wreesmann, B Singh - Surgical oncology clinics of North America, 2008 - Elsevier
Thyroid cancer constitutes a progressive continuum of disease ranging from indolent well-
differentiated carcinomas to aggressive poorly differentiated carcinomas and universally …

Signaling pathways in thyroid cancer

S Jin, YT Yang, W Bao - Vitamins and Hormones, 2018 - Elsevier
The morbidity of thyroid cancer is increasing gradually year by year, showing an increasing
tendency in nationality, sex, age, tumor size, and tumor staging. The changes of thyroid cell …

New treatments and shifting paradigms in differentiated thyroid cancer management

WB Carter, JB Tourtelot, JG Savell… - Cancer …, 2011 - journals.sagepub.com
Background Although most thyroid cancer patients have an excellent prognosis, 10% of low-
risk cancers and 25% of high-risk cancers recur, with mortality rates in excess of 50% at 3 …

[HTML][HTML] Advanced differentiated thyroid cancer: A complex condition needing a tailored approach

AM Bulfamante, E Lori, MI Bellini, E Bolis… - Frontiers in …, 2022 - frontiersin.org
Differentiated thyroid cancers (DTCs) are slow-growing malignant tumours, including
papillary and follicular carcinomas. Overall, prognosis is good, although it tends to worsen …

[HTML][HTML] Updates on the management of advanced, metastatic, and radioiodine refractory differentiated thyroid cancer

D Tumino, F Frasca, K Newbold - Frontiers in Endocrinology, 2017 - frontiersin.org
Differentiated thyroid cancer (DTC) accounts for 95% of all thyroid cancers and is generally
an indolent tumor, treated effectively with surgery, radioactive iodine, and thyroid-stimulating …