Intrathoracic retention of insoluble hyaluronic acid and its absorption process in rats

A Uemura, S Ogawa, R Tanaka - The International Journal …, 2020 - journals.sagepub.com
Background: Post-thoracotomy adhesions are frequent postoperative complications. It has
been reported that insoluble hyaluronic acid may prevent adhesions. Materials and …

Turnover of hyaluronan in the rabbit pleural space

SJ Allen, RE Fraser, UB Laurent… - Journal of Applied …, 1992 - journals.physiology.org
Hyaluronan influences lung fluid balance. The clearance of lung hyaluronan by way of the
pulmonary lymphatics and the pleural space is increased when fluid flux into the interstitium …

Prevention of postoperative intrapleural adhesion of the thoracotomy incision by a bioresorbable membrane in the rat adhesion model.

A Tanaka, T Abe, A Matsuura - … : official journal of the Association of …, 2000 - europepmc.org
For the purpose of reducing the risk of lung injury while separating adhesions in repeated
pulmonary resections, the inhibitory effect of hyaluronate based bioresorbable membrane …

Prevention of postoperative pericardial adhesions with a hyaluronic acid coating solution: Experimental safety and efficacy studies

JD Mitchell, R Lee, GT Hodakowski, K Neya… - The Journal of Thoracic …, 1994 - Elsevier
Postoperative pericardial adhesions complicate reoperative cardiac procedures. Topical
application of solutions containing hyaluronic acid have been shown to reduce adhesions …

[HTML][HTML] Development of an anti-adhesive membrane for use in video-assisted thoracic surgery

A Uemura, T Fukayama, T Tanaka… - … journal of medical …, 2018 - ncbi.nlm.nih.gov
Background: The need to prevent postoperative adhesions after surgery has been
considered a significant challenge in thoracic surgery, especially with the advent of video …

Pleural tissue hyaluronan produced by postmortem ventilation in rabbits

PM Wang, SJ Lai-Fook - Lung, 2000 - Springer
We developed a method that used Alcian blue bound to hyaluronan to measure pleural
hyaluronan in rabbits postmortem. Rabbits were killed, then ventilated with 21% O 2–5% CO …

Assessment of the subcutaneous degradation process of insoluble hyaluronic acid in rats

A Uemura, M Takiguchi, K Funakoshi, Y Noishiki… - Biochemical and …, 2018 - Elsevier
Insoluble hyaluronic acid (IHA) may prevent adhesions by forming a physical barrier during
the period when postoperative adhesions form. This study was performed to verify the …

Effect of increased hydrostatic pressure on lymphatic elimination of hyaluronan from sheep lung

L Lebel, L Smith, B Risberg… - Journal of applied …, 1988 - journals.physiology.org
The effects of increased hydrostatic pressure on the concentrations of hyaluronan
(hyaluronic acid) in lung lymph and serum were investigated in awake sheep with a cannula …

[HTML][HTML] Prevention of pleural adhesions using a membrane containing polyethylene glycol in rats

V Karacam, A Onen, A Sanli, D Gurel… - … journal of medical …, 2011 - ncbi.nlm.nih.gov
Background: Recurrent thoracotomies regardless of the cause are not a rare occurrence.
However, each thoracotomy results in adhesion to some extent. This adhesions increase …

Reduction in experimental pericardial adhesions using a hyaluronic acid bioabsorbable membrane

JD Mitchell, R Lee, K Neya… - European journal of …, 1994 - academic.oup.com
Various materials have been suggested for pericardial closure followingcardiac surgery to
limit postoperative adhesion formation. Unfortunately, these devices have caused difficulties …