MetaboSignal is an R package that allows merging metabolic and signaling pathways
reported in the Kyoto Encyclopaedia of Genes and Genomes (KEGG). It is a network-based …

Background The genetic regulation of metabolic phenotypes (ie, metabotypes) in type 2
diabetes mellitus occurs through complex organ-specific cellular mechanisms and networks …

Attempts have been made to reveal the true nature of a range of puzzling diseases within
gastroenterology and hepatology using different kinds of omics, namely genomics …

Metabolomic data sets provide a direct read-out of cellular phenotypes and are increasingly
generated to study biological questions. Previous work, by us and others, revealed the …

Metabolism is intertwined with various cellular processes, including controlling cell fate,
influencing tumorigenesis, participating in stress responses and more. Metabolism is a …

MetaboNetworks is a tool to create custom sub-networks in Matlab using main reaction pairs
as defined by the Kyoto Encyclopaedia of Genes and Genomes and can be used to explore …

An epistatic interaction between two genes occurs when the phenotypic impact of one gene
depends on another gene, often exposing a functional association between them. Due to …

Molecular interaction maps (MIMs) are static graphical representations depicting complex
biochemical networks that can be formalized using one of the Systems Biology Graphical …

BioCyc. org is a genomic resource that contains more than 7600 Pathway/Genome
Databases (PGDBs) for organisms whose genomes have been completely sequenced …

Metabolic pathways are an important part of systems biology research since they illustrate
complex interactions between metabolites, enzymes, and regulators. Pathway maps are …