Novel methods and technologies for the evaluation of drug outcomes and policies

B Adamson, A Makady, G Sarri, O Mohamed… - Frontiers in …, 2024 - frontiersin.org
Globally, providing quality, equitable healthcare by accelerating patient access to new,
promising health technologies while balancing the impact of their increased expenditures …

Join FDA/PhUSE Working Groups to help harness the power of computational science

CK Cooper - Therapeutic Innovation & Regulatory Science, 2012 - search.proquest.com
Earlier this year, the FDA and PhUSE cast their own wide net to solve common informatics
needs and challenges by calling on all interested parties from across the pharmaceutical …

[PDF][PDF] Data-driven transformation in drug discovery

S Surae - Drug Discovery, 2018 - ddw-online.com
Informatics success in the drug development arena. These technologies have significantly
increased the speed and breadth of research processes that may be implemented …

Data science, AI, and machine learning in drug development

H Yang - 2022 - books.google.com
The confluence of big data, artificial intelligence (AI), and machine learning (ML) has led to a
paradigm shift in how innovative medicines are developed and healthcare delivered. To fully …

Providing data science support for systems pharmacology and its implications to drug discovery

T Hart, L Xie - Expert opinion on drug discovery, 2016 - Taylor & Francis
Introduction: The conventional one-drug-one-target-one-disease drug discovery process
has been less successful in tracking multi-genic, multi-faceted complex diseases. Systems …

Perspective on the challenges and opportunities of accelerating drug discovery with artificial intelligence

JP Santa Maria Jr, Y Wang, LM Camargo - Frontiers in Bioinformatics, 2023 - frontiersin.org
Technology has long been a driver of innovation and improvement in drug discovery
(Gershell and Atkins, 2003; Pina, et al., 2009). Advancements within fields such as chemical …

Exploring AI-driven approaches to drug discovery and development

PB Acharjee, B Ghai, M Elangovan… - The Scientific …, 2023 - scientifictemper.com
The integration of artificial intelligence (AI) into drug discovery and development has
ushered in a transformative era in pharmaceutical research. The research explores the …

Integrity, standards, and QC-related issues with big data in pre-clinical drug discovery

JF Brothers II, M Ung, R Escalante-Chong… - Biochemical …, 2018 - Elsevier
The tremendous expansion of data analytics and public and private big datasets presents an
important opportunity for pre-clinical drug discovery and development. In the field of life …

BERT-based natural language processing of drug labeling documents: a case study for classifying drug-induced liver injury risk

Y Wu, Z Liu, L Wu, M Chen, W Tong - Frontiers in Artificial Intelligence, 2021 - frontiersin.org
Background & Aims: The United States Food and Drug Administration (FDA) regulates a
broad range of consumer products, which account for about 25% of the United States …

Variation in adverse drug events of opioids in the United States

EY Liu, KL McCall, BJ Piper - Frontiers in Pharmacology, 2023 - frontiersin.org
Background: The United States (US) ranks high, nationally, in opioid consumption. The
ongoing increase in the misuse and mortality amid the opioid epidemic has been …