GAS41 mediates proliferation and GEM chemoresistance via H2A.Z.2 and Notch1 in pancreatic cancer
S Han, C Cao, R Liu, YF Yuan, L Pan, M Xu, C Hu… - Cellular Oncology, 2022 - Springer
Purpose GAS41 is a YEATS domain protein that binds to acetylated histone H3 to promote
the chromatin deposition of H2A. Z in non-small cell lung cancer. The role of GAS41 in …
the chromatin deposition of H2A. Z in non-small cell lung cancer. The role of GAS41 in …
Gas7 attenuates hepatocellular carcinoma progression and chemoresistance through the PI3K/Akt signaling pathway
WF Liu, QW Zhang, B Quan, F Zhang, M Li, SX Lu… - Cellular …, 2023 - Elsevier
Growth arrest-specific gene 7 (Gas7) was involved in various cellular functions, although its
specific roles and molecular mechanisms in hepatocellular carcinoma (HCC) remained …
specific roles and molecular mechanisms in hepatocellular carcinoma (HCC) remained …
Downregulation of gas5 increases pancreatic cancer cell proliferation by regulating CDK6
X Lu, Y Fang, Z Wang, J Xie, Q Zhan, X Deng… - Cell and tissue …, 2013 - Springer
Recent studies have revealed that long non-coding RNAs (lncRNAs) play important roles in
cancer biology and that lncRNA gas5 (growth arrest-specific 5) regulates breast cancer cell …
cancer biology and that lncRNA gas5 (growth arrest-specific 5) regulates breast cancer cell …
Development of potent dimeric inhibitors of GAS41 YEATS domain
GAS41 is an emerging oncogene overexpressed and implicated in multiple cancers,
including non-small cell lung cancer (NSCLC). GAS41 is a dimeric protein that contains the …
including non-small cell lung cancer (NSCLC). GAS41 is a dimeric protein that contains the …
Gas6 induces cancer cell migration and epithelial–mesenchymal transition through upregulation of MAPK and Slug
Y Lee, M Lee, S Kim - Biochemical and biophysical research …, 2013 - Elsevier
Binding of Gas6 to Axl (Gas6/Axl axis) alters cellular functions, including migration, invasion,
proliferation, and survival. However, the molecular mechanisms underlying Gas6-mediated …
proliferation, and survival. However, the molecular mechanisms underlying Gas6-mediated …
GAS5 inhibits gastric cancer cell proliferation partly by modulating CDK6
X Guo, K Deng, H Wang, J Xia, T Shan… - Oncology research and …, 2015 - karger.com
Introduction: As it is not clear whether growth arrest-specific 5 (GAS5) inhibits gastric cancer
(GC) cell proliferation by regulating cell cycle, we analyzed the effect of GAS5 on cell cycle …
(GC) cell proliferation by regulating cell cycle, we analyzed the effect of GAS5 on cell cycle …
Blockade of stromal Gas6 alters cancer cell plasticity, activates NK cells, and inhibits pancreatic cancer metastasis
Pancreatic ductal adenocarcinoma (PDA) is one of the deadliest cancers due to its
aggressive and metastatic nature. PDA is characterized by a rich tumor stroma with …
aggressive and metastatic nature. PDA is characterized by a rich tumor stroma with …
LncRNA GAS5 Regulates Gemcitabine Resistance in Pancreatic Carcinoma by Targeting miRNA-21
K Huang, G Yang - Annals of Clinical & Laboratory Science, 2023 - Assoc Clin Scientists
Objective Gemcitabine is the first-line drug for chemotherapy of pancreatic cancer. However,
owing to the inherent and acquired resistance, gemcitabine does not change obviously the …
owing to the inherent and acquired resistance, gemcitabine does not change obviously the …
Overexpression of growth-arrest-specific transcript 5 improved cisplatin sensitivity in hepatocellular carcinoma through sponging miR-222
P Zhao, X Cui, L Zhao, L Liu, D Wang - DNA and Cell Biology, 2020 - liebertpub.com
Long noncoding RNA growth-arrest-specific transcript 5 (GAS5) has been proved to play a
crucial role in cancer chemoresistance. However, the function of GAS5 and its underlying …
crucial role in cancer chemoresistance. However, the function of GAS5 and its underlying …
Overexpression of GAS6 promotes cell proliferation and invasion in bladder cancer by activation of the PI3K/AKT pathway
S Mao, Y Wu, R Wang, Y Guo, D Bi, W Ma… - OncoTargets and …, 2020 - Taylor & Francis
Background Growth arrest-specific 6 (GAS6) is a secreted vitamin K-dependent protein
abnormally expressed in various human tumor tissues and can activate the receptor Tyro3 …
abnormally expressed in various human tumor tissues and can activate the receptor Tyro3 …