[HTML][HTML] GAS5 functions as a ceRNA to regulate hZIP1 expression by sponging miR-223 in clear cell renal cell carcinoma

X Dong, C Kong, X Liu, J Bi, Z Li, Z Li… - American Journal of …, 2018 - ncbi.nlm.nih.gov
Several studies have shown that low expression of hZIP1 is closely associated with many
human cancers, including clear cell renal cell carcinoma (ccRCC). In this study, we aimed to …

CYP2C8 regulated by GAS5/miR-382-3p exerts anti-cancerous properties in liver cancer

K Li, Y Chen - Cancer biology & therapy, 2020 - Taylor & Francis
ABSTRACT A cornucopia of literatures has characterized the involvement of a host of
functional molecules in liver cancer. Herein, according to online datasets, we found that …

[HTML][HTML] LncRNA GAS6-AS2 facilitates tumor growth and metastasis of hepatocellular carcinoma by activating the PI3K/AKT/FoxO3a signaling pathway

C Liang, L Pang, Y Ke, W Ji, J Xiong… - International journal of …, 2019 - ncbi.nlm.nih.gov
The morbidity and mortality of hepatocellular carcinoma (HCC) are growing yearly. Several
reports emphasize the importance of long non-coding RNAs (lncRNAs) in HCC. This paper …

G9A promotes gastric cancer metastasis by upregulating ITGB3 in a SET domain-independent manner

L Hu, M Zang, H Wang, B Zhang, Z Wang, Z Fan… - Cell death & …, 2018 - nature.com
Tumor metastasis is the leading cause of death in patients with advanced gastric cancer
(GC). Limited therapeutic regimens are available for this condition, which is associated with …

Gas6 and the receptor tyrosine kinase Axl in clear cell renal cell carcinoma

A Gustafsson, AK Boström, B Ljungberg, H Axelson… - PloS one, 2009 - journals.plos.org
Background The molecular biology of renal cell carcinoma (RCC) is complex and not fully
understood. We have recently found that the expression of the receptor tyrosine kinase Axl …

[HTML][HTML] ISG15 Promotes Progression and Gemcitabine Resistance of Pancreatic Cancer Cells Through ATG7

Y Meng, L Bian, M Zhang, P Zhou, S Zhang… - … Journal of Biological …, 2024 - ncbi.nlm.nih.gov
Chemoresistance is an obstacle of improving pancreatic cancer (PC) prognosis. However,
the biological function of ISG15 in PC and whether it correlates with the resistance to …

Low long noncoding RNA growth arrest‐specific transcript 5 expression in the exosomes of lung cancer cells promotes tumor angiogenesis

Y Cheng, X Dai, T Yang, N Zhang, Z Liu… - Journal of …, 2019 - Wiley Online Library
Angiogenesis plays a key role in the development and progression of lung cancer. Recent
studies have found that tumor cells can stimulate angiogenesis by secreting exosomes …

Identification of a Novel Gene, GASC1, within an Amplicon at 9p23–24 Frequently Detected in Esophageal Cancer Cell Lines

ZQ Yang, I Imoto, Y Fukuda, A Pimkhaokham… - Cancer research, 2000 - AACR
In a recent study, we identified frequent amplification of DNA copy number at chromosome
9p23–24 in cell lines derived from esophageal squamous cell carcinomas (ESCs), using …

Long noncoding RNA GAS5 suppresses the migration and invasion of hepatocellular carcinoma cells via miR-21

L Hu, H Ye, G Huang, F Luo, Y Liu, Y Liu, X Yang… - Tumor Biology, 2016 - Springer
Long noncoding RNAs (lncRNAs) are aberrantly expressed in various cancers. Although
lncRNA GAS5 (growth arrest-specific transcript 5) has been characterized as a tumor …

Hypoxia stabilizes GAS6/Axl signaling in metastatic prostate cancer

A Mishra, J Wang, Y Shiozawa, S McGee, J Kim… - Molecular cancer …, 2012 - AACR
The receptor tyrosine kinase Axl is overexpressed in a variety of cancers and is known to
play a role in proliferation and invasion. Previous data from our laboratory indicate that Axl …