Cells have evolved multiple mechanisms for maintaining cholesterol homeostasis, and,
among these, ATP-binding cassette protein A1 (ABCA1)-mediated cholesterol efflux is …

Cholesterol is an essential component of eukaryotic cells; at the same time, however,
hyperaccumulation of cholesterol is harmful. Therefore, the ABCA1 gene, the product of …

Liver X receptors (LXR) are oxysterol-activated nuclear receptors that play a central role in
reverse cholesterol transport through up-regulation of ATP-binding cassette transporters …

The ATP-binding cassette transporter ABCA1 is essential for high density lipoprotein (HDL)
formation and considered rate-controlling for reverse cholesterol transport. Expression of the …

ABCA1 is an ATP binding cassette transporter that plays an essential role in cholesterol and
phospholipid efflux and HDL biogenesis. ABCA1 expression in macrophage cells is subject …

Liver X receptors (LXRs) regulate the expression of genes involved in cholesterol and fatty
acid homeostasis, including the genes for ATP-binding cassette transporter A1 (ABCA1) and …

ATP-binding cassette transporter 1 (ABC1) mediates the active efflux of cholesterol from
cells to apolipoproteins. To study the mechanisms of regulation of ABC1 gene expression …

Oxysterol binding to liver X receptors (LXR) increases the transcription of genes involved in
cholesterol efflux and disposal, such as ABCA1 (ATP-binding cassette transporter A1). Other …

Objective—Release of cellular cholesterol and phospholipid mediated by helical
apolipoprotein and ATP-binding cassette transporter (ABC) A1 is a major source of plasma …

The ABC transporter ABCG1 (ATP binding cassette transporter G1), expressed in
macrophages, liver, and other tissues, has been implicated in the efflux of cholesterol to high …