The immune system is a tremendously complicated and important system, whose central
players, the lymphocytes, are able to recognize specific foreign invaders (antigens) with their …

The vertebrate adaptive immune system, with its learning and memory capabilities, is a
particularly rich example of the complexity of biological systems. The most difficult challenge …

The successful immune response to given antigen is manifested by elimination of antigen;
generation of antibody forming cells and production of antibody (if humoral response) or …

A mathematical model of B lymphocyte differentiation, based on experimental results, has
been developed. The model focuses on the role of antigen in initiating and regulating B cell …

The development of T-lymphocytes (T cells) constitute one of the basic and most vital
processes in immunology. Conventional mathematical models, being based on the systems …

Interest in mathematical immunology has been growing. This is reflected in the several
monographs that have been published and the conferences that have been held lately …

Mathematical models of antibody response Page 1 Folia Mierobiol. 25, 430--438 (1980)
Mathematical Models of Antibody Response P. KL~,IN Deparbment of Iramunology, Institute of …

We consider the long lived pool of B and T cells that recirculate through blood, tissues and
the lymphatic system of an animal with body mass M. We derive scaling rules (allometric …

We present a simple model based on microscopic automata to describe the clonal
expansion process. The model is based on a repertoire of antigens and T lymphocytes …

Abstract Systems of differentiating cells are often regarded by experimental biologists as
unidirectional processes, in which cells spend a fixed time at each successive …