Rapid Screening Technique for Class 1 Integrons inEnterobacteriaceae and Nonfermenting Gram-Negative Bacteria and Its Use in Molecular Epidemiology

AJ Maguire, DFJ Brown, JJ Gray… - Antimicrobial agents …, 2001 - Am Soc Microbiol
ABSTRACT A screening technique for integrons in members of the family
Enterobacteriaceae and nonfermenting gram-negative bacteria by real-time PCR is …

Class I integrons in Gram-negative isolates from different European hospitals and association with decreased susceptibility to multiple antibiotic compounds.

P Martinez-Freijo, AC Fluit, FJ Schmitz… - The Journal of …, 1998 - academic.oup.com
Class I integrons are associated with carriage of genes encoding resistance to antibiotics.
Expression of inserted resistance genes within these structures can be poor and, as such …

Molecular epidemiology of integron-associated antibiotic resistance genes in clinical isolates of Enterobacteriaceae

B SALLEN, A RAJOHARISON… - Microbial Drug …, 1995 - liebertpub.com
The epidemiology of integron-mediated antibiotic-resistant genes in clinical enterobacteria
from a single location was investigated. Forty-nine isolates (kindly provided by Dr. D. Sirot …

Many Class I Integrons Comprise Distinct Stable Structures Occurring in Different Species ofEnterobacteriaceae Isolated from Widespread Geographic Regions in …

P Martinez-Freijo, AC Fluit, FJ Schmitz… - Antimicrobial agents …, 1999 - Am Soc Microbiol
Three sizes of inserted regions of DNA (800, 1,000, and 1,500 bp) were shown to be
common among class I integrons in unrelated clinical isolates of Enterobacteriaceae from …

Integrons and Gene Cassettes in theEnterobacteriaceae

PA White, CJ McIver, WD Rawlinson - Antimicrobial agents and …, 2001 - Am Soc Microbiol
Integrons were detected in 59 of 120 (49%) urinary isolates of Enterobacteriaceae by PCR
using degenerate primers targeted to conserved regions of class 1, 2, and 3 integrase …

Multiplex PCR for screening of integrons in bacterial lysates

B Dillon, L Thomas, G Mohmand, A Zelynski… - Journal of microbiological …, 2005 - Elsevier
Bacterial integrons are a useful PCR amplification target in epidemiological surveys of
bacterial antibiotic resistance, and a variety of primers have been published. We describe …

PCR mapping of integrons reveals several novel combinations of resistance genes

C Levesque, L Piche, C Larose… - Antimicrobial agents and …, 1995 - Am Soc Microbiol
The integron is a new type of mobile element which has evolved by a site-specific
recombinational mechanism. Integrons consist of two conserved segments of DNA …

Integrons: adding another threat to the use of antibiotic therapy

SR Norrby - Clinical Infectious Diseases, 2005 - academic.oup.com
In this issue of Clinical Infectious Diseases, Nijssen et al.[1] describe the spread in 2
intensive care units (ICUs) of Enterobacteriaceae strains that carried integrons coding for …

Increased Prevalence of Class I Integrons inEscherichia coli, Klebsiella Species, andEnterobacter Species Isolates over a 7-Year Period in a German University …

FJ Schmitz, D Hafner, R Geisel… - Journal of clinical …, 2001 - Am Soc Microbiol
The prevalence of integrons in five enterobacterial species was analyzed in 900 blood
culture isolates from 1993, 1996, and 1999. Remarkably, the prevalence increased from …

Class 1 integrons, gene cassettes, mobility, and epidemiology

AC Fluit, FJ Schmitz - European Journal of Clinical Microbiology and …, 1999 - Springer
Integrons are genetic elements that, although unable to move themselves, contain gene
cassettes that can be mobilized to other integrons or to secondary sites in the bacterial …