[HTML][HTML] Over expression of PPP2R2C inhibits human glioma cells growth through the suppression of mTOR pathway

Y Fan, L Chen, J Wang, Q Yao, J Wan - FEBS letters, 2013 - Elsevier
Abstract PPP2R2C encodes a gamma isoform of the subunit B55 subfamily, which is a
regulatory subunit of Protein phosphatase type 2A (PP2A). Our study shows that PPP2R2C …

PPP2R5A: a multirole protein phosphatase subunit in regulating cancer development

Z Mao, C Liu, X Lin, B Sun, C Su - Cancer Letters, 2018 - Elsevier
Protein phosphatase 2, regulatory subunit B (B56), alpha isoform (PPP2R5A) is one of the
regulatory subunits of the protein phosphatase 2A (PP2A), which is a major member of …

Serine/threonine protein phosphatase-5 accelerates cell growth and migration in human glioma

X Zhi, H Zhang, C He, Y Wei, L Bian, G Li - Cellular and molecular …, 2015 - Springer
Glioma is the most common type of primary central nervous system tumor. Ser/Thr protein
phosphatase 5 (PP5) has been shown to regulate multiple signaling cascades that suppress …

Protein phosphatase 2 regulatory subunit B''Alpha silencing inhibits tumor cell proliferation in liver cancer

H Chen, J Xu, P Wang, Q Shu, L Huang, J Guo… - Cancer …, 2019 - Wiley Online Library
Aim To explore the effects of protein phosphatase 2 regulatory subunit B''Alpha (PPP2R3A)
on the proliferation and migration of liver cancer cells. Methods Expression of PPP2R3A in …

[HTML][HTML] PPP2R2D, a regulatory subunit of protein phosphatase 2A, promotes gastric cancer growth and metastasis via mechanistic target of rapamycin activation

S Yu, L Li, Q Wu, N Dou, Y Li… - … Journal of Oncology, 2018 - spandidos-publications.com
Abstract Protein phosphatase 2A (PP2A) is an essential serine/threonine protein
phosphatase that regulates the basic activities of eukaryotes by dephosphorylating its …

Protein phosphatase 4 catalytic subunit is overexpressed in glioma and promotes glioma cell proliferation and invasion

M Li, X Li, S Xu, P Xue, QZ Li, Q Lu, Q Jia, L Zhang, X Li… - Tumor Biology, 2016 - Springer
Protein phosphatase 4 catalytic subunit (PP4C) has been identified to be overexpressed in
various solid cancers. However, to date, the role of PP4C in glioma remains elusive. In the …

Disruption of serine/threonine protein phosphatase 5 inhibits tumorigenesis of urinary bladder cancer cells

M Chen, JM Lv, JQ Ye, XG Cui… - International …, 2017 - spandidos-publications.com
Serine/threonine protein phosphatase 5 (PPP5C) is a member of the protein
serine/threonine phosphatase family and has been shown to participate in multiple signaling …

PR55α subunit of protein phosphatase 2A supports the tumorigenic and metastatic potential of pancreatic cancer cells by sustaining hyperactive oncogenic signaling

AL Hein, P Seshacharyulu, S Rachagani, YM Sheinin… - Cancer research, 2016 - AACR
The protein phosphatase 2 (PP2A) holoenzyme consists of a catalytic subunit, a scaffold
subunit, and a regulatory subunit. Based on loss-of-function analysis using PP2A catalytic …

Characterization of a human regulatory subunit of protein phosphatase 3 gene (PPP3RL) expressed specifically in testis

L Liu, J Zhang, J Yuan, Y Dang, C Yang, X Chen… - Molecular biology …, 2005 - Springer
Abstract Protein phosphatase 3 (PPP3, formerly PP2B, Calcineurin), a serine/threonine
protein phosphatase, is a heterodimer composed of one catalytic subunit (PPP3C …

Somatic mutations and genetic polymorphisms of the PPP1R3 gene in patients with several types of cancers

S Takakura, T Kohno, K Shimizu, S Ohwada… - Oncogene, 2000 - nature.com
Recently, we found nonsense and missense mutations of the PPP1R3 (protein phosphatase
1, regulatory subunit 3) gene in diverse human cancer cell lines and primary lung …