[HTML][HTML] Severe sepsis: variation in resource and therapeutic modality use among academic centers

DT Yu, E Black, KE Sands, JS Schwartz, PL Hibberd… - Critical care, 2003 - Springer
Background Treatment of severe sepsis is expensive, often encompassing a number of
discretionary modalities. The objective of the present study was to assess intercenter …

[HTML][HTML] Characteristics, management, and in-hospital mortality among patients with severe sepsis in intensive care units in Japan: the FORECAST study

T Abe, H Ogura, A Shiraishi, S Kushimoto, D Saitoh… - Critical Care, 2018 - Springer
Background Sepsis is a leading cause of death and long-term disability in developed
countries. A comprehensive report on the incidence, clinical characteristics, and evolving …

Epidemiology of severe sepsis in India: an update

S Todi, S Chatterjee, S Sahu, M Bhattacharyya - Critical Care, 2010 - Springer
Methods All patients admitted to the ITU were screened daily for SIRS, organ dysfunction
and severe sepsis as defined by the ACCP and SCCM. Patient with severe sepsis were …

[HTML][HTML] Model for predicting short-term mortality of severe sepsis

C Adrie, A Francais, A Alvarez-Gonzalez, R Mounier… - Critical Care, 2009 - Springer
Introduction To establish a prognostic model for predicting 14-day mortality in ICU patients
with severe sepsis overall and according to place of infection acquisition and to sepsis …

[HTML][HTML] Lack of evidence for qualitative treatment by disease severity interactions in clinical studies of severe sepsis

WL Macias, DR Nelson, M Williams, R Garg, J Janes… - Critical Care, 2005 - Springer
Introduction The design of clinical trials of interventions aimed at reducing mortality in
patients with severe sepsis assumes that the relative treatment effect of the intervention is …

[HTML][HTML] Incidence, organ dysfunction and mortality in severe sepsis: a Spanish multicentre study

J Blanco, A Muriel-Bombín, V Sagredo, F Taboada… - Critical care, 2008 - Springer
Introduction Sepsis is a leading cause of admission to non-cardiological intensive care units
(ICUs) and the second leading cause of death among ICU patients. We present the first …

[HTML][HTML] Prevalence and incidence of severe sepsis in Dutch intensive care units

A van Gestel, J Bakker, CPWM Veraart, BA van Hout - Critical care, 2004 - Springer
Introduction Severe sepsis is a dreaded consequence of infection and necessitates
intensive care treatment. Severe sepsis has a profound impact on mortality and on hospital …

[HTML][HTML] Reducing mortality in severe sepsis with the implementation of a core 6-hour bundle: results from the Portuguese community-acquired sepsis study (SACiUCI …

T Cardoso, AH Carneiro, O Ribeiro, A Teixeira-Pinto… - Critical Care, 2010 - Springer
Introduction To evaluate the impact of compliance with a core version of the Surviving
Sepsis Campaign 6-hour bundle on 28 days mortality. Methods Cohort, multi-centre …

[HTML][HTML] Implementation of sepsis bundles in public hospitals in Brazil: a prospective study with heterogeneous results

FR Machado, EM Ferreira, P Schippers, IC de Paula… - Critical Care, 2017 - Springer
Background Public hospitals in emerging countries pose a challenge to quality improvement
initiatives in sepsis. Our objective was to evaluate the results of a quality improvement …

[HTML][HTML] Mortality and quality of life in the five years after severe sepsis

BH Cuthbertson, A Elders, S Hall, J Taylor… - Critical Care, 2013 - Springer
Introduction Severe sepsis is associated with high levels of morbidity and mortality, placing a
high burden on healthcare resources. We aimed to study outcomes in the five years after …