Phorbol ester-induced alteration of differentiation and proliferation in human hematopoietic tumor cell lines: relationship to the presence and subcellular distribution of …
K Forsbeck, K Nilsson, A Hansson, G Skoglund… - Cancer research, 1985 - AACR
The intracellular translocation of protein kinase C (PKC) from the soluble to the membranous
fraction has been shown previously to correlate with biological activity of phorbol esters in …
fraction has been shown previously to correlate with biological activity of phorbol esters in …
Immunocytochemical evidence for phorbol ester-induced protein kinase C translocation in HL60 cells
M Shoji, PR Girard, GJ Mazzei, WR Vogler… - … and biophysical research …, 1986 - Elsevier
The ability of tumor promoting 12-O-tetradecanoylphorbol-13-acetate (TPA) to redistribute
protein kinase C in human promyelocytic leukemic HL60 cells was investigated. It was found …
protein kinase C in human promyelocytic leukemic HL60 cells was investigated. It was found …
Immunocytochemical evidence for phorbol ester-induced directional translocations of protein kinase C in HL60, K562, CHO, and E7SKS cells: possible role in …
PR Girard, VL Stevens, PJ Blackshear, AH Merrill Jr… - Cancer research, 1987 - AACR
The effects of phorbol ester 12-O-tetradecanoylphorbol-13-acetate (TPA) on the directions of
protein kinase C (PKC) translocation in two leukemic cell lines (HL60 and K562) and two …
protein kinase C (PKC) translocation in two leukemic cell lines (HL60 and K562) and two …
Translocation of protein kinase C in human leukemia cells susceptible or resistant to differentiation induced by phorbol 12-myristate 13-acetate.
Y Homma, CB Henning-Chubb… - Proceedings of the …, 1986 - National Acad Sciences
We investigated the possible relationship between the susceptibility of cells to differentiation
induced by phorbol 12-myristate 13-acetate (PMA) and the subcellular translocation of …
induced by phorbol 12-myristate 13-acetate (PMA) and the subcellular translocation of …
Temporal changes in intracellular distribution of protein kinase C during differentiation of human leukemia HL60 cells induced by phorbol ester
Z Kiss, E Deli, JF Kuo - FEBS letters, 1988 - Wiley Online Library
Immunocytochemical methods were used to study protein kinase C (PKC) distribution in
HL60 cells during the entire course of 12‐O‐tetradecanoylphorbol‐13‐acetate (TPA) …
HL60 cells during the entire course of 12‐O‐tetradecanoylphorbol‐13‐acetate (TPA) …
Partial down‐regulation of protein kinase C reverses the growth inhibitory effect of phorbol esters on HepG2 cells
V Duronio, BE Huber, S Jacobs - Journal of cellular physiology, 1990 - Wiley Online Library
Phorbol ester treatment of HepG2, a human tumorigenic cell line, caused rapid
morphological changes characterized by a flattening and spreading of the cells that …
morphological changes characterized by a flattening and spreading of the cells that …
Activation by phorbol esters of protein kinase C in MCF-7 human breast cancer cells
M Issandou, F Bayard, JM Darbon - FEBS letters, 1986 - Elsevier
Exposure of MCF-7 human breast cancer cells to the phorbol ester 12-O-
tetradecanoylphorbol-13-acetate (TPA) leads to the inhibition of cell proliferation. We …
tetradecanoylphorbol-13-acetate (TPA) leads to the inhibition of cell proliferation. We …
Effects of chronic phorbol ester treatment on protein kinase C activity, content, and gene expression in the human monoblastoid U937 cell.
DK Ways, W Qin, TO Garris, J Chen, E Hao… - Cell Growth & …, 1994 - europepmc.org
Immediate and sustained signal transduction is involved in mediating phorbol ester-induced
changes in growth and differentiation. Activation of protein kinase C (PKC) is the initial step …
changes in growth and differentiation. Activation of protein kinase C (PKC) is the initial step …
Phorbol esters induce both intracellular translocation and down-regulation of protein kinase C in MCF-7 cells
JM Darbon, M Issandon, F Delassus… - … and biophysical research …, 1986 - Elsevier
Exposure of MCF-7 human breast cancer cells to phorbol ester 12-O-tetradecanoyl-13-
acetate (TPA) results in a complete inhibition of cell proliferation. We investigated the effects …
acetate (TPA) results in a complete inhibition of cell proliferation. We investigated the effects …
Differential responsiveness to phorbol esters correlates with differential expression of protein kinase C in KG-1 and KG-1a human myeloid leukemia cells
WC Hooper, RT Abraham, CL Ashendel… - … et Biophysica Acta (BBA …, 1989 - Elsevier
The KG-1 myeloid leukemia cell line differentiates into macrophages in response to 12-O-
tetradecanoylphorbol 13-acetate (TPA), while its spontaneous variant, the KG-1a cell line, is …
tetradecanoylphorbol 13-acetate (TPA), while its spontaneous variant, the KG-1a cell line, is …