Placental origins of chronic disease
Epidemiological evidence links an individual's susceptibility to chronic disease in adult life to
events during their intrauterine phase of development. Biologically this should not be …
events during their intrauterine phase of development. Biologically this should not be …
Placenta, evolution and lifelong health
The intrauterine environment has an important influence on lifelong health, and babies who
grew poorly in the womb are more likely to develop chronic diseases in later life. Placental …
grew poorly in the womb are more likely to develop chronic diseases in later life. Placental …
Role of the placenta in fetal programming: underlying mechanisms and potential interventional approaches
Adverse influences during fetal life alter the structure and function of distinct cells, organ
systems or homoeostatic pathways, thereby 'programming'the individual for an increased …
systems or homoeostatic pathways, thereby 'programming'the individual for an increased …
[HTML][HTML] The programming power of the placenta
AN Sferruzzi-Perri, EJ Camm - Frontiers in physiology, 2016 - frontiersin.org
Size at birth is a critical determinant of life expectancy, and is dependent primarily on the
placental supply of nutrients. However, the placenta is not just a passive organ for the …
placental supply of nutrients. However, the placenta is not just a passive organ for the …
[HTML][HTML] Paternal epigenetic influences on placental health and their impacts on offspring development and disease
SS Bhadsavle, MC Golding - Frontiers in Genetics, 2022 - frontiersin.org
Our efforts to understand the developmental origins of birth defects and disease have
primarily focused on maternal exposures and intrauterine stressors. Recently, research into …
primarily focused on maternal exposures and intrauterine stressors. Recently, research into …
Biological features of placental programming
KL Thornburg, K Kolahi, M Pierce, A Valent, R Drake… - Placenta, 2016 - Elsevier
The placenta is a key organ in programming the fetus for later disease. This review outlines
nine of many structural and physiological features of the placenta which are associated with …
nine of many structural and physiological features of the placenta which are associated with …
Placental adaptations to the maternal–fetal environment: implications for fetal growth and developmental programming
I Sandovici, K Hoelle, E Angiolini… - Reproductive biomedicine …, 2012 - Elsevier
The placenta is a transient organ found in eutherian mammals that evolved primarily to
provide nutrients for the developing fetus. The placenta exchanges a wide array of nutrients …
provide nutrients for the developing fetus. The placenta exchanges a wide array of nutrients …
The placenta is a programming agent for cardiovascular disease
KL Thornburg, PF O'tierney, S Louey - Placenta, 2010 - Elsevier
Cardiovascular disease remains the number one killer in western nations in spite of declines
in death rates following improvements in clinical care. It has been 20 years since David …
in death rates following improvements in clinical care. It has been 20 years since David …
Sex-specific placental responses in fetal development
CS Rosenfeld - Endocrinology, 2015 - academic.oup.com
The placenta is an ephemeral but critical organ for the survival of all eutherian mammals
and marsupials. It is the primary messenger system between the mother and fetus, where …
and marsupials. It is the primary messenger system between the mother and fetus, where …
Maternal influences on placental development
J Aplin - Seminars in Cell & Developmental Biology, 2000 - Elsevier
Epidemiological evidence suggests that size at birth may affect health in later life. The
growth of the fetus may be adversely affected by a suboptimal maternal environment …
growth of the fetus may be adversely affected by a suboptimal maternal environment …