Peptaibiotics are a group of membrane active peptides of fungal origin. They typically
contain α-aminoisobutyric acid (Aib; 1-letter code, U) and other non-coded residues (Toniolo …

Peptaibiotics, non-ribosomally synthetized peptides from various ascomycetes, are uniquely
characterized by di-alkylated α-amino acids, a rigid helical conformation, and membrane …

Trichogin GA IV, isolated from the fungus Trichoderma longibrachiatum, is the prototype of
lipopeptaibols, the sub-class of short-length peptaibiotics exhibiting membrane-modifying …

Peptaibols are peculiar peptides produced by fungi as weapons against other
microorganisms. Previous studies showed that peptaibols are promising peptide-based …

New classes of antibacterial drugs are urgently needed to address the global issue of
antibiotic resistance. In this context, peptaibols are promising membrane-active peptides …

The lipopeptaibol trichogin GA IV is a natural, non-ribosomally synthesized, antimicrobial
peptide remarkably resistant to the action of hydrolytic enzymes. This feature may be …

A set of three analogs of the 10‐residue, membrane‐active lipopeptaibiotic trichogin GA IV,
labeled with the promising 4‐nitrophenylalanine IR absorption probe for local polarity, was …

Today's shortage of effective antimicrobial agents can be overcome by using antimicrobial
peptides, which are produced naturally by a wide range of organisms, including …

Trichogin GA IV is a short‐length (10‐amino acid long), mostly hydrophobic, peptaibiotic
with an N‐terminal fatty acyl chain and a C‐terminal 1, 2‐amino alcohol. A cardinal role of …

Fighting resistance to antibiotics and chemotherapeutics has brought bioactive peptides to
the fore. Peptaibols are short α-aminoisobutyric acid-containing peptides produced by …