Wilms' tumour, or nephroblastoma, is a common childhood tumour that is intimately linked to
early kidney development and is often associated with persistent embryonic renal tissue and …

Wilms tumor or nephroblastoma is a pediatric kidney cancer arising from pluripotent
embryonic renal precursors. Multiple genetic loci have been linked to Wilms tumorigenesis; …

Wilms' tumor (nephroblastoma) represents a unique example of an aberrant kidney
formation that can result from mutations in a tumor suppressor gene, Wilms' tumor 1 (WT1) …

The Wilms tumor protein WT1 is an essential factor for kidney development. In humans,
mutations in WT1 lead to Wilms tumor, a pediatric kidney cancer as well as to developmental …

Kidney development has been studied over the past sixty years as a model of embryonic
induction during organogenesis. Wilms' tumor-1 (WT1), that encodes a transcription factor …

The human Wilms' tumor predisposition gene, WT1, is a Cys-His zinc finger polypeptide
which appears to be a transcription factor controlling gene expression during embryonic …

Wilms' tumor is a childhood kidney tumor that is a striking example of the way that cancer
may arise through development gone awry. A proportion of these tumors develop as a result …

abstract The Wilms' tumor 1 (wt1) gene is one of at least three genes that are involved in the
development of Wilms' tumor, a pediatric kidney cancer. The expression pattern of the gene …

The Wilms' tumor suppressor gene wt1 encodes a zinc‐finger transcription factor that plays
an important role in the development of the mammalian genitourinary system. Mutations in …

Normal development of the kidney is a highly complex process that requires precise
orchestration of proliferation, differentiation, and apoptosis. In the past few years, a number …