Although memantine blocks sodium currents and produces local skin anesthesia, spinal
anesthesia with memantine is unknown. The purpose of the study was to evaluate the local …

BACKGROUND: Memantine blocks N-methyl-D-aspartate receptors and the Na+ current,
one principal mechanism of local anesthesia. Until now, no study mentioned that memantine …

The purpose of the experiment was to evaluate the local anesthetic effect of rimantadine in
spinal anesthesia. Rimantadine in a dose-dependent fashion was constructed after …

The purpose of the study is to find subcutaneous equianalgesic doses of memantine,
amantadine and bupivacaine and use these doses to quantify the cardiovascular and …

The aims of the study were to evaluate the spinal anesthetic effect of caramiphen and also
assess spinal anesthetic interactions of caramiphen with lidocaine. Lidocaine, a common …

Though promazine and chlorpromazine elicited cutaneous anesthesia, no study of spinal
anesthesia with chlorpromazine and promazine has been reported. This study was to …

The purpose of this study was to estimate the local anesthetic effect of orphenadrine, an anti-
muscarinic agent, in spinal anesthesia and its comparison with the local anesthetic …

Background The aim of the study was to compare the proposed spinal anesthetic effect of
ifenprodil, an a1 adrenergic receptor antagonist, with that of the long-acting local anesthetic …

The purpose of this study was to examine the effect of epinephrine as adjuvant for
memantine or lidocaine as an infiltrative anesthetic. Using a rat model of cutaneous trunci …

We aimed to compare the hypothesized local anesthetic action of amantadine (1‐
adamantanamine) with that of the known local anesthetic mepivacaine. Motor …