Chimerism and minimal residual disease monitoring after reduced intensity conditioning (RIC) allogeneic transplantation

JA Perez-Simon, D Caballero, M Diez-Campelo… - Leukemia, 2002 - nature.com
Since graft-versus-leukemia (GVL) is the main weapon for disease eradication after reduced
intensity conditioning (RIC) allogeneic SCT, the availability of sensitive and specific …

Comparative serial quantitative measurements of chimaerism following unmanipulated allogeneic transplantation of peripheral blood stem cells and bone marrow

G Miflin, CJ Stainer, GI Carter, JL Byrne… - British journal of …, 1999 - Wiley Online Library
Serial samples were collected from 38 patients following allogeneic transplantation using
either unmanipulated peripheral blood stem cells (PBSC)(n= 18) or bone marrow (BM)(n …

Real-time biallelic polymorphism–polymerase chain reaction for chimerism monitoring of hematopoietic stem cell transplantation relapsed patients

DP Chen, CP Tseng, WT Wang, MC Wang, SH Tsai… - Clinica Chimica …, 2011 - Elsevier
BACKGROUND: An accurate analysis of chimerism kinetics permits early detection of
hematopoietic stem cell transplantation (HSCT) in patients with high risks of graft-versus …

Mixed hematopoietic chimerism after allogeneic bone marrow transplantation: the impact of quantitative PCR analysis for prediction of relapse and graft rejection in …

P Bader, W Hölle, T Klingebiel… - Bone marrow …, 1997 - nature.com
It still remains unclear whether patients with mixed hematopoietic chimerism (MC) after
allogeneic bone marrow transplantation (allo-BMT) have an increased risk of developing …

The mythological chimera and new era of relapse prediction post-transplant

SO Ciurea, A Kothari, S Sana, MM Al Malki - Blood Reviews, 2023 - Elsevier
Allogeneic hemopoietic stem cell transplantation is the treatment of choice for high-risk or
relapsed acute leukemia. However, unfortunately, relapse post-transplant continues to be …

Mixed chimaerism; detection and significance following BMT.

SR McCann, M Lawler - Bone marrow transplantation, 1993 - europepmc.org
Residual recipient haematopoietic cells may coexist with donor haemopoietic tissue
following BMT. This is known as mixed chimaerism. The incidence of mixed chimaerism …