Conventional grafting techniques for bone regeneration are currently being replaced by
tissue engineering approaches of using 3D biomimetic materials. Of these biomaterials …

Tissue is vital to the organization of multicellular organisms, because it creates the different
organs and provides the main scaffold for body shape. The quest for effective methods to …

The regeneration of bone tissue is the main purpose of most therapies in dental medicine.
For bone regeneration, calcium phosphate (CaP)-based substitute materials based on …

Bone provides mechanical support, and flexibility to the body as a structural frame work
along with mineral storage, homeostasis, and blood pH regulation. The repair and/or …

Extensive bone defect repair remains a clinical challenge, since ideal implantable scaffolds
require the integration of excellent biocompatibility, sufficient mechanical strength and high …

Bone defects and diseases are devastating, and can lead to severe functional deficits or
even permanent disability. Nevertheless, orthopedic implants and scaffolds can facilitate the …

Titanium (Ti) and its alloys are promising metal materials in orthopedic field, mainly due to
their good mechanical properties, corrosion resistance and biocompatibility. However, the …

Bone fractures and critical-size bone defects are significant public health issues, and clinical
treatment outcomes are closely related to the intrinsic properties of the utilized implant …

Background: Natural bone is a complex and hierarchical structure. Bone possesses an
extracellular matrix that has a precise nano-sized environment to encourage osteoblasts to …

Large-sized bone defects are a great challenge in clinics and considerably impair the quality
of patients' daily life. Tissue engineering strategies using cells, scaffolds, and bioactive …