Chalcones: an update on cytotoxic and chemoprotective properties
ML Go, X Wu, XL Liu - Current medicinal chemistry, 2005 - ingentaconnect.com
Chalcone is a unique template that is associated with several biological activities. In this
review, an update of the cytotoxic and chemoprotective activities of chalcones is provided …
review, an update of the cytotoxic and chemoprotective activities of chalcones is provided …
Recent advances in therapeutic chalcones
L Ni, CQ Meng, JA Sikorski - Expert Opinion on Therapeutic Patents, 2004 - Taylor & Francis
Naturally-occurring and synthetic chalcone compounds have shown promising biological
activity and safety profiles and have the potential to be developed as, or more properly …
activity and safety profiles and have the potential to be developed as, or more properly …
Chalcone derivatives: role in anticancer therapy
Y Ouyang, J Li, X Chen, X Fu, S Sun, Q Wu - Biomolecules, 2021 - mdpi.com
Chalcones (1, 3-diaryl-2-propen-1-ones) are precursors for flavonoids and isoflavonoids,
which are common simple chemical scaffolds found in many naturally occurring compounds …
which are common simple chemical scaffolds found in many naturally occurring compounds …
Pharmacological properties of chalcones: a review of preclinical including molecular mechanisms and clinical evidence
Chalcones are among the leading bioactive flavonoids with a therapeutic potential
implicated to an array of bioactivities investigated by a series of preclinical and clinical …
implicated to an array of bioactivities investigated by a series of preclinical and clinical …
Trends in utilization of the pharmacological potential of chalcones
DI Batovska, IT Todorova - Current clinical pharmacology, 2010 - ingentaconnect.com
Chalcones (1, 3-diaryl-2-propen-1-ones) are open chain flavonoids that are widely
biosynthesized in plants. They are important for the pigmentation of flowers and, hence, act …
biosynthesized in plants. They are important for the pigmentation of flowers and, hence, act …
Heterocyclic chalcone analogues as potential anticancer agents
Chalcones, aromatic ketones and enones acting as the precursor for flavonoids such as
Quercetin, are known for their anticancer effects. Although, parent chalcones consist of two …
Quercetin, are known for their anticancer effects. Although, parent chalcones consist of two …
Chalcones derivatives acting as cell cycle blockers: potential anti cancer drugs?
A Boumendjel, X Ronot, J Boutonnat - Current drug targets, 2009 - ingentaconnect.com
Chalcones (1, 3-diphenylpropen-1-ones) are naturally occurring compounds belonging to
the flavonoid family and are largely investigated in various therapeutic area and especially …
the flavonoid family and are largely investigated in various therapeutic area and especially …
Chalcones: Promising therapeutic agents targeting key players and signaling pathways regulating the hallmarks of cancer
AA WalyEldeen, S Sabet, HM El-Shorbagy… - Chemico-Biological …, 2023 - Elsevier
The need for innovative anticancer treatments with high effectiveness and low toxicity is
urgent due to the development of malignancies that are resistant to chemotherapeutic …
urgent due to the development of malignancies that are resistant to chemotherapeutic …
In vitro evaluation of newly developed chalcone analogues in human cancer cells
R De Vincenzo, C Ferlini, M Distefano… - Cancer chemotherapy …, 2000 - Springer
Purpose: Among flavonoids, chalcones have been identified as interesting compounds
having chemopreventive and antitumor properties. We studied a panel of newly developed …
having chemopreventive and antitumor properties. We studied a panel of newly developed …
Chalcones as promising lead compounds on cancer therapy
AJ Leon-Gonzalez, N Acero… - Current medicinal …, 2015 - ingentaconnect.com
Chalcones constitute a group of phenolic compounds that command an increasing interest
on cancer research. Natural chalcones are widespread through the plant kingdom. The most …
on cancer research. Natural chalcones are widespread through the plant kingdom. The most …